Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5160589 | 0.84 | TSHR (0.53) | RAB9APOLBGAASMN1; SMN2TSHR | |
| SCHEMBL428389 | 0.79 | RAB9A (0.53) | RAB9APOLBGAASMN1; SMN2TSHR | |
| SCHEMBL5162812 | 0.79 | TSHR (0.47) | RAB9APOLBGAASMN1; SMN2TSHR | |
| SCHEMBL5162856 | 0.79 | RAB9A (0.57) | RAB9APOLBGAASMN1; SMN2TSHR | |
| SCHEMBL13222147 | 0.78 | KDM4E (0.54) | POLBGAAKDM4E | |
| SCHEMBL13041458 | 0.77 | TSHR (0.53) | RAB9APOLBGAASMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL29099350 | 0.77 | RAB9A (0.51) | RAB9APOLBGAASMN1; SMN2TSHR | |
| SCHEMBL5160090 | 0.77 | ALDH1A1 (0.52) | RAB9APOLBGAASMN1; SMN2TSHR | |
| SCHEMBL9664550 | 0.77 | TSHR (0.56) | RAB9APOLBGAASMN1; SMN2TSHR | |
| SCHEMBL12847003 | 0.77 | RAB9A (0.60) | RAB9APOLBGAASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114133402-A | Coumarin carbazole photoinitiator capable of initiating polymerization by free radicals, preparation method and application thereof | 同济大学 | 2022-03-04 | — | — | CN | disclosed |
| CN-114031622-A | Coumarin carbazole photosensitizer capable of being polymerized by cationic initiation, preparation method and application thereof | 同济大学 | 2022-02-11 | — | — | CN | disclosed |
| US-8293899-B2 | Ketone transfer hydrogenation of stereoisomerically enriched 3-heteroaryl-3-oxocarboxylic esters by reducing 3-heteroaryl-3-hydroxycarboxylic esters in the presence of a ruthenium-containing catalyst, an amine and formic acid and/or formates | LANXESS DEUTSCHLAND GMBH (DE) | 2012-10-23 | — | — | US | disclosed |
| EP-1340746-B1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | SALTIGO GMBH (DE) | 2007-02-28 | — | — | EP | disclosed |
| US-20030225274-A1 | Process for reducing 3-heteroaryl-3-oxopropionic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-04 | — | — | US | disclosed |
| EP-1340746-A1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | BAYER AG (DE) | 2003-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225274-A1 | Process for reducing 3-heteroaryl-3-oxopropionic acid derivatives | GRHPR, HPD, HAAO | RAB9A 3428/4885POLB 2040/4885GAA 1272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.