Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 6/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5161206 | 0.95 | ITGB1 (0.38) | ITGB1ITGA4PTGDR2HPGDSMN1; SMN2 | |
| SCHEMBL5162922 | 0.88 | ITGB1 (0.33) | ITGB1ITGA4PTGDR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL5424270 | 0.86 | ALDH1A1 (0.32) | ITGB1ITGA4PTGDR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL5162560 | 0.83 | ITGB1 (0.38) | ITGB1ITGA4PTGDR2ALDH1A1HTT | |
| SCHEMBL5161415 | 0.82 | ITGB1 (0.37) | ITGB1ITGA4PTGDR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL5160306 | 0.82 | ITGB1 (0.52) | ITGB1ITGA4ALDH1A1MEN1KMT2A | |
| SCHEMBL14371600 | 0.80 | ITGA4 (0.45) | ITGB1ITGA4PTGDR2HPGDSMN1; SMN2 | |
| SCHEMBL14400262 | 0.80 | ITGA4 (0.45) | ITGB1ITGA4PTGDR2HPGDSMN1; SMN2 | |
| SCHEMBL14371599 | 0.76 | ITGA4 (0.47) | ITGB1ITGA4PTGDR2C5AR1PIN1 | |
| SCHEMBL14400211 | 0.76 | ITGA4 (0.47) | ITGB1ITGA4PTGDR2C5AR1PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1757602-A1 | VLA-4 INHIBITOR | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | VCAM1, ITGB4, ITGA4 | ITGB1 9/4885ITGA4 3/4885PTGDR2 2692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.