Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | PTPRF | P10586 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717008 | 0.80 | ALDH1A1 (0.40) | ALDH1A1HSD17B10HPGDBCL2L1HDAC4 | |
| SCHEMBL6630718 | 0.77 | ABL1 (0.50) | ALDH1A1KMT2APTPN1CYP2A6SMN1; SMN2 | |
| SCHEMBL487401 | 0.76 | ALDH1A1 (0.48) | ALDH1A1HSD17B10HPGDBCL2L1HDAC4 | |
| SCHEMBL14471688 | 0.76 | BACE1 (0.50) | ALDH1A1HSD17B10HPGDBCL2L1HDAC4 | |
| SCHEMBL5949997 | 0.76 | CASP1 (0.41) | CASP1ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL8602846 | 0.76 | CA12 (0.42) | CASP1ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL8340887 | 0.76 | CYP2A6 (0.40) | CASP1ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL11635485 | 0.76 | ALDH1A1 (0.36) | ALDH1A1HSD17B10HPGDBCL2L1HDAC4 | |
| SCHEMBL8627009 | 0.74 | ALDH1A1 (0.39) | ALDH1A1HSD17B10HPGDBCL2L1HDAC4 | |
| SCHEMBL4886483 | 0.73 | LMNA (0.50) | CASP1ALDH1A1HSD17B10HPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841491-B2 | Method for producing fluorene derivative | TAOKA CHEMICAL CO., LTD. (JP) | 2014-09-23 | — | — | US | disclosed |
| EP-2420485-A1 | METHOD FOR PRODUCING FLUORENE DERIVATIVE | Taoka Chemical Co., Ltd. (JP) | 2012-02-22 | — | — | EP | disclosed |
| US-20120029244-A1 | METHOD FOR PRODUCING FLUORENE DERIVATIVE | TAOKA CHEMICAL CO., LTD. (JP) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029244-A1 | METHOD FOR PRODUCING FLUORENE DERIVATIVE | ADH1A, AFF2, AFF1 | CASP1 2923/4885ALDH1A1 119/4885HSD17B10 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.