SCHEMBL5162029

SCHEMBL5162029

Nc1ccc(N)c(CC(O)Cl)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.38
RECQL P46063 2/20 0.38
MEN1 O00255 2/20 0.38
USP2 O75604 2/20 0.38
POLB P06746 2/20 0.38
MAPT P10636 2/20 0.38
KMT2A Q03164 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
APEX1 P27695 2/20 0.38
PKM P14618 1/20 0.38
BLM P54132 1/20 0.38
MCL1 Q07820 1/20 0.38
ACHE P22303 3/20 0.38
ALDH1A1 P00352 5/20 0.37
CYP3A4 P08684 4/20 0.37
TSHR P16473 3/20 0.37
CASP1 P29466 3/20 0.37
ALOX15 P16050 2/20 0.37
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6570822 0.83 PRKCI (0.37) THRBRECQLMEN1USP2POLB
Hydrochloric Acid SCHEMBL26979264 0.82 ACHE (0.41) THRBRECQLMEN1USP2POLB
SCHEMBL28856683 0.82 PRKCI (0.36) THRBRECQLMEN1USP2POLB
SCHEMBL3839781 0.80 PRKCI (0.39) THRBRECQLMEN1USP2POLB
SCHEMBL2877038 0.78 CYP3A4 (0.38) THRBRECQLMEN1USP2POLB
SCHEMBL6678293 0.77 PRKCI (0.41) THRBRECQLMEN1USP2POLB
Sulfuric Acid SCHEMBL5822225 0.76 ALDH1A1 (0.50) THRBRECQLMEN1USP2POLB
SCHEMBL24625576 0.75 CASP1 (0.33) THRBRECQLMEN1USP2POLB
SCHEMBL30227313 0.75 MAPT (0.41) MAPTTDP1ACHEALDH1A1TSHR
SCHEMBL2339661 0.75 MAPT (0.41) MAPTTDP1ACHEALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1557157-B1 Composition for the dyeing of human hair KPSS KAO GMBH (DE) 2007-03-07 EP claimed
US-7070628-B2 Composition for the dyeing of human hair KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2006-07-04 US claimed
US-7070627-B2 Composition for the dyeing of human hair KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2006-07-04 US claimed
EP-1428503-B1 Composition for the dyeing of human hair KPSS KAO GMBH (DE) 2006-05-10 EP claimed
US-6991660-B2 Composition for the dyeing of human hair KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2006-01-31 US claimed
US-6986794-B2 Composition of the dyeing of human hair KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2006-01-17 US claimed
EP-1374840-B1 Composition for the dyeing of human hair KPSS KAO GMBH (DE) 2005-10-19 EP claimed
EP-1374841-B1 Composition for dyeing of human hair KPSS KAO GMBH (DE) 2005-10-19 EP claimed
EP-1557157-A1 Composition for the dyeing of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2005-07-27 EP claimed
US-20040139561-A1 Composition of the dyeing of human hair KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2004-07-22 US claimed
EP-1428503-A2 Composition for the dyeing of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2004-06-16 EP claimed
EP-1374841-A2 Composition for dyeing of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2004-01-02 EP claimed
EP-1374840-A2 Composition for the dyeing of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2004-01-02 EP claimed
US-20030233716-A1 Composition for the dyeing of human hair KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2003-12-25 US claimed
US-20030233715-A1 Composition for the dyeing of human hair KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2003-12-25 US claimed
EP-1557157-B1 Composition for the dyeing of human hair KPSS KAO GMBH (DE) 2007-03-07 EP disclosed
US-7070627-B2 Composition for the dyeing of human hair KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2006-07-04 US disclosed
US-20030233716-A1 Composition for the dyeing of human hair KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2003-12-25 US disclosed
US-20030233716-A1 Composition for the dyeing of human hair KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2003-12-25 US disclosed
US-20030233715-A1 Composition for the dyeing of human hair KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2003-12-25 US disclosed