SCHEMBL6570822

SCHEMBL6570822

Nc1ccc(N)c(CC(O)O)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.37
MAPT P10636 3/20 0.36
THRB P10828 2/20 0.36
RECQL P46063 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
MEN1 O00255 2/20 0.36
POLB P06746 2/20 0.36
KMT2A Q03164 2/20 0.36
USP2 O75604 1/20 0.36
PKM P14618 1/20 0.36
APEX1 P27695 1/20 0.36
BLM P54132 1/20 0.36
MCL1 Q07820 1/20 0.36
ACHE P22303 3/20 0.36
TSHR P16473 4/20 0.35
CASP1 P29466 3/20 0.35
ALDH1A1 P00352 3/20 0.35
CYP3A4 P08684 3/20 0.35
ALOX15 P16050 2/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL5822225 0.91 ALDH1A1 (0.50) PRKCIMAPTTHRBRECQLTDP1
SCHEMBL28856683 0.85 PRKCI (0.36) PRKCIMAPTTHRBRECQLTDP1
SCHEMBL3839781 0.83 PRKCI (0.39) PRKCIMAPTTHRBRECQLTDP1
SCHEMBL5162029 0.83 THRB (0.38) PRKCIMAPTTHRBRECQLTDP1
SCHEMBL28368492 0.83 CASP1 (0.38) PRKCIMAPTTHRBRECQLTDP1
Hydrochloric Acid SCHEMBL26979264 0.82 ACHE (0.41) PRKCIMAPTTHRBRECQLTDP1
SCHEMBL2877038 0.82 CYP3A4 (0.38) PRKCIMAPTTHRBRECQLTDP1
SCHEMBL6678293 0.80 PRKCI (0.41) PRKCIMAPTTHRBRECQLTDP1
SCHEMBL33610 0.79 ALOX15 (0.46) MAPTTHRBTDP1PKMTSHR
SCHEMBL24625576 0.78 CASP1 (0.33) PRKCIMAPTTHRBRECQLTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250017837-A1 AGENT FOR OXIDATIVELY DYEING KERATIN FIBERS HENKEL AG & CO. KGAA (DE) 2025-01-16 US claimed
EP-2785323-A2 AGENT AND METHOD FOR COLOURING KERATIN FIBRES GW Cosmetics GmbH (AT) 2014-10-08 EP claimed
WO-2013078492-A2 AGENT AND METHOD FOR COLOURING KERATIN FIBRES GW COSMETICS GMBH (AT) 2013-06-06 WO claimed
US-5182213-A Coupling a Phenylenediamine and a Naphthol MILES INC. (US) 1993-01-26 US claimed
EP-0504663-A1 Peroxidase indicator system for basic media Bayer Corporation (US) 1992-09-23 EP claimed
JP-5095797-A None JP disclosed
US-20250025395-A1 Means for Oxidatively Dyeing Keratin Fibers HENKEL AG & CO. KGAA (DE) 2025-01-23 US disclosed
US-10179099-B2 Decolorization of dyed keratin fibers HENKEL AG & CO. KGAA (DE) 2019-01-15 US disclosed
US-20170326055-A1 DECOLORIZATION OF DYED KERATIN FIBERS HENKEL AG & CO. KGAA (DE) 2017-11-16 US disclosed
EP-2787989-A1 GLUCURONOLACTONE DERIVATES AS SELF-TANNING SUBSTANCES Merck Patent GmbH (DE) 2014-10-15 EP disclosed
WO-2013083225-A1 GLUCURONOLACTONE DERIVATES AS SELF-TANNING SUBSTANCES MERCK PATENT GMBH (DE) 2013-06-13 WO disclosed
CN-1761517-A Mixing device HENKEL KGAA (DE) 2006-04-19 CN disclosed
CN-1205910-C Yellow hair coloring compositions with improved long wear characteristics P & P CLAROL INC (US) 2005-06-15 CN disclosed
EP-1443889-A1 OXIDATION COLOURING AGENT BASED ON BICYCLIC DEVELOPER COMPONENTS Henkel Kommanditgesellschaft auf Aktien (DE) 2004-08-11 EP disclosed
CN-1462183-A Yellow hair coloring compositions with improved long wear characteristics P & G CLAROL INC (US) 2003-12-17 CN disclosed
WO-2003041672-A1 OXIDATION COLOURING AGENT BASED ON BICYCLIC DEVELOPER COMPONENTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-05-22 WO disclosed
JP-H0595797-A METHOD USING PEROXIDASE INDICATOR FOR BASIC MEDIA AND ANALYTICAL DEVICE MILES INC 1993-04-20 JP disclosed
US-5182213-A Coupling a Phenylenediamine and a Naphthol MILES INC. (US) 1993-01-26 US disclosed
EP-0504663-A1 Peroxidase indicator system for basic media Bayer Corporation (US) 1992-09-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250017837-A1 AGENT FOR OXIDATIVELY DYEING KERATIN FIBERS KRT18, OAT, SQOR PRKCI 978/4885MAPT 568/4885THRB 4028/4885
US-10179099-B2 Decolorization of dyed keratin fibers KRT18, DDR1, DDR2 PRKCI 1113/4885MAPT 3269/4885THRB 3912/4885
US-20170326055-A1 DECOLORIZATION OF DYED KERATIN FIBERS KRT18, DDR1, DDR2 PRKCI 1113/4885MAPT 3269/4885THRB 3912/4885
US-20250025395-A1 Means for Oxidatively Dyeing Keratin Fibers KRT18, SQOR, ADH4 PRKCI 1429/4885MAPT 833/4885THRB 3379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.