SCHEMBL5162072

SCHEMBL5162072

CC(=O)Nc1ccccc1Sc1nnn[nH]1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
PDE7A Q13946 1/20 0.43
HPGD P15428 1/20 0.41
ITGB3 P05106 1/20 0.40
ITGAV P06756 1/20 0.40
ITGA2B P08514 1/20 0.40
CYP2C9 P11712 1/20 0.39
CRBN Q96SW2 1/20 0.39
MAPT P10636 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
POLB P06746 1/20 0.38
CYP2C19 P33261 1/20 0.38
KDM4E B2RXH2 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
CETP P11597 2/20 0.37
MAPK1 P28482 1/20 0.37
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10703572 0.87 TDP1 (0.39) ALDH1A1HPGDCYP2C9MAPTTDP1
SCHEMBL9304520 0.83 AR (0.42) ALDH1A1HPGDMAPTTDP1L3MBTL1
SCHEMBL11806175 0.83 PTPN1 (0.39) ALDH1A1HPGDMAPTTDP1L3MBTL1
SCHEMBL9670035 0.78 PRKAG1 (0.36) ALDH1A1MAPTPOLBKDM4ELMNA
SCHEMBL10431594 0.78 ALDH1A1 (0.59) ALDH1A1PDE7AHPGDMAPTTDP1
SCHEMBL11525920 0.74 GAA (0.44) ALDH1A1HPGDCRBNMAPTTDP1
SCHEMBL7592576 0.73 KDR (0.47) ALDH1A1ITGB3ITGAVITGA2BCRBN
SCHEMBL12892206 0.72 ALDH1A1 (0.57) ALDH1A1HPGDCYP2C9CYP2C19KDM4E
SCHEMBL5199349 0.72 PNP (0.36) ALDH1A1HPGDMAPTTDP1POLB
SCHEMBL4938228 0.71 KMT2A (0.62) ALDH1A1HPGDMAPTPOLBCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1306719-B1 Silver halide photographic material showing improved latent image stability AGFA GEVAERT (BE) 2007-03-07 EP claimed
US-7118849-B2 Photothermographic materials with UV absorbing compounds EASTMAN KODAK COMPANY (US) 2006-10-10 US disclosed
US-7112399-B2 Photothermographic materials with opaque crossover control means EASTMAN KODAK COMPANY (US) 2006-09-26 US disclosed
US-20060040222-A1 Photothermographic materials with opaque crossover control means EASTMAN KODAK COMPANY 2006-02-23 US disclosed
US-20060040221-A1 Photothermographic materials with UV absorbing support EASTMAN KODAK COMPANY 2006-02-23 US disclosed
US-20060019206-A1 Photothermographic materials with UV absorbing compounds EASTMAN KODAK COMPANY 2006-01-26 US disclosed
EP-0985964-B1 Photographic material having enhanced light absorption EASTMAN KODAK CO (US) 2005-02-23 EP disclosed
US-6331385-B1 TABULAR SILVER HALIDE PARTICLES WITH INTERIOR LAYER OF SENSITIZING DYE AND EXTERIOR LAYER OF CYANINE, MEROCYANINE, ARYLIDENE, STYRYL, OXONOL, ANTHRAQUINONE, TRIPHENYLMETHANE, AZO, AZO-METHINE, AND/OR COUMARIN DYE EASTMAN KODAK COMPANY 2001-12-18 US disclosed
EP-0994388-A1 Medical diagnostic film for soft tissue imaging (II) EASTMAN KODAK COMPANY (US) 2000-04-19 EP disclosed
EP-0985964-A1 Photographic material having enhanced light absorption EASTMAN KODAK COMPANY (US) 2000-03-15 EP disclosed
US-6037112-A FILMS CONTAINING RADIATION-SENSITIVE SILVER HALIDE EMULSIONS FOR CREATING MEDICAL DIAGNOSTIC IMAGES OF SOFT TISSUE WHEN IMAGEWISE EXPOSED WITH AN INTENSIFYING SCREEN EASTMAN KODAK COMPANY (US) 2000-03-14 US disclosed
EP-0686273-A1 PREPARATION OF A SILVER CHLOROBROMIDE PHOTOGRAPHIC EMULSION AND USE IN COLOUR NEGATIVE PROCESSES KODAK-PATHE (FR) 1995-12-13 EP disclosed
WO-1995017701-A1 PREPARATION OF A SILVER CHLOROBROMIDE PHOTOGRAPHIC EMULSION AND USE IN COLOUR NEGATIVE PROCESSES KODAK-PATHE (FR) 1995-06-29 WO disclosed