SCHEMBL9304520

SCHEMBL9304520

O=C(Nc1ccccc1Sc1nnn[nH]1)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.42
TP53 P04637 2/20 0.41
MAPT P10636 2/20 0.41
HTT P42858 2/20 0.41
JAK2 O60674 1/20 0.41
KLK7 P49862 1/20 0.41
CETP P11597 1/20 0.40
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PARP14 Q460N5 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
GLA P06280 1/20 0.35
PKM P14618 1/20 0.35
HPGD P15428 1/20 0.35
BLM P54132 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10703572 0.84 TDP1 (0.39) MAPTCETPMEN1KMT2ATDP1
SCHEMBL5162072 0.83 ALDH1A1 (0.44) MAPTCETPTDP1ALDH1A1L3MBTL1
SCHEMBL27688958 0.75 TDP1 (0.62) MAPTHTTCETPMEN1KMT2A
SCHEMBL9574413 0.74 CETP (0.69) TP53MAPTHTTJAK2KLK7
SCHEMBL9517036 0.72 NOTUM (0.40) ARMAPT
SCHEMBL9574421 0.71 CETP (0.51) ARTP53MAPTHTTJAK2
SCHEMBL9131197 0.70 PDK1 (0.53) TP53MAPTHTTJAK2KLK7
SCHEMBL28770107 0.70 L3MBTL1 (0.60) TP53MAPTHTTCETPMEN1
SCHEMBL27688984 0.70 TDP1 (0.49) TP53MAPTHTTJAK2KLK7
SCHEMBL9670035 0.70 PRKAG1 (0.36) MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0602742-A2 Photographic material and process employing a development inhibitor releasing compound containing a fluorinated carbon alpha to an amide group EASTMAN KODAK COMPANY (US) 1994-06-22 EP disclosed
US-5283163-A Color photography; sharpness; good interimage results; quality EASTMAN KODAK COMPANY (US) 1994-02-01 US disclosed