SCHEMBL7592576

SCHEMBL7592576

CC(=O)Nc1cccc(Sc2nnn[nH]2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 2/20 0.47
MAPT P10636 2/20 0.46
HSD17B10 Q99714 3/20 0.44
ALDH1A1 P00352 2/20 0.44
CYP1A2 P05177 1/20 0.44
ITGB3 P05106 1/20 0.42
ITGAV P06756 1/20 0.42
ITGA2B P08514 1/20 0.42
RAB9A P51151 3/20 0.41
POLB P06746 2/20 0.41
NR4A1 P22736 1/20 0.41
SMN1; SMN2 Q16637 5/20 0.41
NPC1 O15118 2/20 0.41
TSHR P16473 1/20 0.41
CRBN Q96SW2 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
GRM4 Q14833 1/20 0.40
MEN1 O00255 1/20 0.40
TP53 P04637 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11525920 0.83 GAA (0.44) MAPTHSD17B10ALDH1A1RAB9APOLB
SCHEMBL13836493 0.80 ALDH1A1 (0.61) KDRMAPTHSD17B10ALDH1A1CYP1A2
SCHEMBL6923199 0.79 CRBN (0.46) KDRMAPTHSD17B10ALDH1A1CYP1A2
SCHEMBL21552590 0.74 NOTUM (0.41) MAPTALDH1A1SMN1; SMN2CRBNL3MBTL1
SCHEMBL6694019 0.74 MAPT (0.59) MAPTHSD17B10ALDH1A1CYP1A2RAB9A
SCHEMBL17324145 0.73 ALDH1A1 (0.61) MAPTHSD17B10ALDH1A1CYP1A2RAB9A
SCHEMBL5162072 0.73 ALDH1A1 (0.44) MAPTALDH1A1ITGB3ITGAVITGA2B
SCHEMBL5208634 0.72 MAPT (0.70) MAPTHSD17B10ALDH1A1CYP1A2RAB9A
SCHEMBL9594853 0.71 TSHR (0.39) HSD17B10ALDH1A1SMN1; SMN2TSHRNAPRT
SCHEMBL10766441 0.71 RXFP1 (0.44) MAPTALDH1A1CYP1A2RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6472134-B1 Silver halide element with improved high temperature storage and sensitivity EASTMAN KODAK COMPANY 2002-10-29 US disclosed
US-6472133-B1 Silver halide element with improved high temperature storage EASTMAN KODAK COMPANY 2002-10-29 US disclosed
US-6472135-B1 Silver halide element with improved high temperature storage and raw stock keeping EASTMAN KODAK COMPANY 2002-10-29 US disclosed
US-6440655-B1 AMIDO COMPOUNDS AS STABILIZERS AND ANTIFOGGANTS COATED ON POLYESTER SUPPORTS EASTMAN KODAK COMPANY 2002-08-27 US disclosed
EP-1164423-A2 Silver halide element with improved high temperature storage EASTMAN KODAK COMPANY (US) 2001-12-19 EP disclosed
EP-0683427-B1 Blue sensitizing dyes with heterocyclic substituents EASTMAN KODAK CO (US) 2001-11-14 EP disclosed
US-6066443-A PROVIDES GOOD SPEED AND IMPROVED COLOR REPRODUCTION; MAXIMUM BLUE SENSITIVITY AT LESS THAN 485 NM. EASTMAN KODAK COMPANY (US) 2000-05-23 US disclosed
EP-0683427-A1 Blue sensitizing dyes with heterocyclic substituents EASTMAN KODAK COMPANY (US) 1995-11-22 EP disclosed