Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of 1-Pentanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL11686153 | 0.89 | ALDH1A1 (0.61) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| Glycerin SCHEMBL28843648 | 0.89 | ALDH1A1 (0.61) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| 1-Hexanol SCHEMBL8330159 | 0.86 | LMNA (0.68) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| Octanol SCHEMBL8395596 | 0.86 | LMNA (0.68) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| Cetostearyl Alcohol SCHEMBL20743362 | 0.86 | LMNA (0.68) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| Dodecanol SCHEMBL1845318 | 0.86 | LMNA (0.68) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| Cetyl Alcohol SCHEMBL3462931 | 0.86 | LMNA (0.68) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| Dodecanol SCHEMBL15053182 | 0.86 | LMNA (0.68) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| Glycerin SCHEMBL1133946 | 0.86 | ALDH1A1 (0.65) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| Glycerin SCHEMBL27560542 | 0.84 | ALDH1A1 (0.61) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9683178-B2 | Process for reducing acidity of hydrocarbon feeds | SUNCOR ENERGY INC. (CA) | 2017-06-20 | — | — | US | disclosed |
| US-9028677-B2 | Demulsifying of hydrocarbon feeds | SUNCOR ENERGY INC. (CA) | 2015-05-12 | — | — | US | disclosed |
| US-20120152807-A1 | PROCESS AND SYSTEM FOR REDUCING ACIDITY OF HYDROCARBON FEEDS | SUNCOR ENERGY INC. (CA) | 2012-06-21 | — | — | US | disclosed |
| US-20120029259-A1 | DEMULSIFYING OF HYDROCARBON FEEDS | SUNCOR ENERGY, INC. (CA) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029259-A1 | DEMULSIFYING OF HYDROCARBON FEEDS | ARNT, AHR, PIGS | SMN1; SMN2 3011/4885LMNA 324/4885ALDH1A1 4216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.