Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075032 | 0.90 | HPGD (0.40) | RAB9AHPGDSMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL206456 | 0.87 | POLB (0.45) | RAB9AHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4869393 | 0.87 | EPHX1 (0.42) | RAB9AHPGDSMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL4084293 | 0.86 | HDAC3 (0.42) | RAB9AHPGDSMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL208660 | 0.85 | PLAAT3 (0.46) | RAB9ASMN1; SMN2OPRM1OPRL1NPC1 | |
| SCHEMBL206704 | 0.84 | SMYD3 (0.39) | RAB9AHPGDSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL2983415 | 0.84 | MEN1 (0.45) | RAB9AHPGDSMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL4048631 | 0.84 | KMT2A (0.51) | RAB9AOPRM1OPRL1ALDH1A1MEN1 | |
| SCHEMBL4084189 | 0.83 | HRH3 (0.40) | RAB9AHPGDSMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL4072191 | 0.82 | HPGD (0.38) | RAB9AHPGDSMN1; SMN2OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751090-A1 | ACID DERIVATIVES OF SUBSTITUTED CYCLOHEXYL-1,4-DIAMINES | Grünenthal GmbH (DE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005110973-A1 | ACID DERIVATIVES OF SUBSTITUTED CYCLOHEXYL-1,4-DIAMINES | Grünenthal GmbH (DE) | 2005-11-24 | — | — | WO | disclosed |