Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL209170 | 0.90 | HPGD (0.35) | HPGDRAB9ASMN1; SMN2ALDH1A1OPRM1 | |
| SCHEMBL206456 | 0.87 | POLB (0.45) | HPGDRAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4075032 | 0.86 | HPGD (0.40) | HPGDRAB9ASMN1; SMN2ALDH1A1OPRM1 | |
| SCHEMBL205912 | 0.84 | HPGD (0.47) | HPGDRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL4084293 | 0.84 | HDAC3 (0.42) | HPGDRAB9ASMN1; SMN2ALDH1A1OPRM1 | |
| SCHEMBL208660 | 0.83 | PLAAT3 (0.46) | RAB9ASMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL207807 | 0.83 | KMT2A (0.37) | RAB9AALDH1A1OPRM1OPRL1MEN1 | |
| SCHEMBL206704 | 0.82 | SMYD3 (0.39) | HPGDRAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL208300 | 0.82 | LMNA (0.50) | RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL5162372 | 0.82 | RAB9A (0.43) | HPGDRAB9ASMN1; SMN2ALDH1A1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |