Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075032 | 0.94 | HPGD (0.40) | HPGDRAB9ASMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL206456 | 0.89 | POLB (0.45) | HPGDRAB9ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL208660 | 0.87 | PLAAT3 (0.46) | RAB9ASMN1; SMN2OPRM1OPRL1TSHR | |
| SCHEMBL5162372 | 0.86 | RAB9A (0.43) | HPGDRAB9ASMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL4072191 | 0.84 | HPGD (0.38) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL208300 | 0.84 | LMNA (0.50) | RAB9AMEN1KMT2ALMNATSHR | |
| SCHEMBL206704 | 0.84 | SMYD3 (0.39) | HPGDRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL205912 | 0.84 | HPGD (0.47) | HPGDRAB9AMEN1KMT2ALMNA | |
| SCHEMBL4865158 | 0.82 | MEN1 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4084112 | 0.82 | HPGD (0.45) | HDAC3HDAC1HDAC2HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |