Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079453 | 0.91 | LMNA (0.43) | HRH3OPRM1OPRL1HPGD | |
| SCHEMBL206402 | 0.88 | ALDH1A1 (0.41) | OPRM1OPRL1ALDH1A1HPGDRAB9A | |
| SCHEMBL207622 | 0.86 | HRH3 (0.45) | HRH3OPRM1OPRL1ALDH1A1HPGD | |
| SCHEMBL209932 | 0.84 | AVPR1A (0.44) | MEN1KMT2A | |
| SCHEMBL4081016 | 0.83 | EPHX2 (0.45) | OPRM1OPRL1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL208694 | 0.83 | AVPR1A (0.41) | ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL5162372 | 0.83 | RAB9A (0.43) | OPRM1OPRL1ALDH1A1HPGDRAB9A | |
| SCHEMBL4080671 | 0.82 | OPRM1 (0.37) | OPRM1OPRL1ALDH1A1HPGDRAB9A | |
| SCHEMBL4075032 | 0.82 | HPGD (0.40) | OPRM1OPRL1ALDH1A1HPGDRAB9A | |
| SCHEMBL4048631 | 0.82 | KMT2A (0.51) | OPRM1OPRL1ALDH1A1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |