Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 9/20 | 0.48 |
| ▸ | MAOA | P21397 | 8/20 | 0.48 |
| ▸ | KIF11 | P52732 | 3/20 | 0.47 |
| ▸ | PTPRZ1 | P23471 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28169917 | 0.84 | MAOB (0.50) | ALDH1A1MAOBMAOAKIF11CYP2A6 | |
| SCHEMBL6001741 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4ETDP1KIF11PTPRZ1 | |
| SCHEMBL19638946 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4ETDP1KIF11PTPRZ1 | |
| SCHEMBL5117424 | 0.77 | AR (0.49) | ALDH1A1KDM4EMAOBMAOAKIF11 | |
| SCHEMBL695548 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4ETDP1KIF11PTPRZ1 | |
| SCHEMBL17870969 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4ETDP1KIF11PTPRZ1 | |
| SCHEMBL1817472 | 0.75 | MAOB (0.56) | ALDH1A1MAOBMAOACYP2A6CA12 | |
| SCHEMBL10978325 | 0.75 | ALDH1A1 (0.61) | ALDH1A1KDM4ETDP1KIF11PTPRZ1 | |
| SCHEMBL10566578 | 0.75 | ENPP2 (0.40) | ALDH1A1KDM4ETDP1MAOBMAOA | |
| SCHEMBL31046876 | 0.75 | ENPP2 (0.40) | ALDH1A1KDM4ETDP1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101250144-A | Preparation method of 4-trifluoro-methylthio benzoic acid | JINTAN LINGYUN CHEMICAL INDUST (CN) | 2008-08-27 | — | — | CN | claimed |
| US-12606522-B2 | Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives | ORSOBIO, INC. (US) | 2026-04-21 | — | — | US | disclosed |
| US-20240409508-A1 | SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES | ORSOBIO, INC. | 2024-12-12 | — | — | US | disclosed |
| CN-118791407-A | Sulfinylamino group benzamide and process for preparing same Sulfonylamino benzamide derivatives | 奥索生物公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-118638096-A | Sulfinylamino group benzamide and process for preparing same Sulfonylamino benzamide derivatives | 奥索生物公司 | 2024-09-13 | — | — | CN | disclosed |
| US-12049439-B2 | Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives | ORSOBIO, INC. (US) | 2024-07-30 | — | — | US | disclosed |
| CN-112204008-B | Sulfonylaminobenzamides and sulfonylaminobenzamide derivatives | 奥索生物公司 | 2024-07-05 | — | — | CN | disclosed |
| EP-3796975-B1 | SULFONYLAMINOBENZAMIDE DERIVATIVES | ORSOBIO INC (US) | 2023-08-30 | — | — | EP | disclosed |
| US-20220055985-A1 | SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES | GILEAD SCIENCES, INC. | 2022-02-24 | — | — | US | disclosed |
| CN-111825580-B | Method for synthesizing aromatic hydrocarbon trifluoromethylthio compound | 南京理工大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-103003266-A | Hydroxyalkylbenzylpyrazoles and their use for the treatment of hyperproliferative and angiogenic diseases | BAYER IP GMBH | 2013-03-27 | — | — | CN | disclosed |
| EP-2569309-A1 | HYDROXYALKYL BENZYL PYRAZOLES, AND USE THEREOF FOR THE TREATMENT OF HYPERPROLIFERATIVE AND ANGIOGENIC DISEASES | Bayer Intellectual Property GmbH (DE) | 2013-03-20 | — | — | EP | disclosed |
| EP-2569312-A1 | SUBSTITUTED HETEROCYCLYL BENZYL PYRAZOLES, AND USE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2013-03-20 | — | — | EP | disclosed |
| US-8299108-B2 | for treatment of hematological/hormone-dependent cancer | NOVARTIS AG (CH) | 2012-10-30 | — | — | US | disclosed |
| US-20120028950-A1 | Substituted heterocyclylbenzylpyrazoles and use thereof | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2012-02-02 | — | — | US | disclosed |
| WO-2011141325-A1 | HYDROXYALKYL BENZYL PYRAZOLES, AND USE THEREOF FOR THE TREATMENT OF HYPERPROLIFERATIVE AND ANGIOGENIC DISEASES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |
| WO-2011141326-A1 | SUBSTITUTED HETEROCYCLYL BENZYL PYRAZOLES, AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |
| CN-101691347-A | Preparation process of 4-(Trifluoromethylthio)benzoyl chloride | BAOQING TANG | 2010-04-07 | — | — | CN | disclosed |
| CN-101250144-A | Preparation method of 4-trifluoro-methylthio benzoic acid | JINTAN LINGYUN CHEMICAL INDUST (CN) | 2008-08-27 | — | — | CN | disclosed |
| CN-101250144-A | Preparation method of 4-trifluoro-methylthio benzoic acid | JINTAN LINGYUN CHEMICAL INDUST (CN) | 2008-08-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220055985-A1 | SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES | STS, SULT2A1, SCN2B | ALDH1A1 245/4885KDM4E 3158/4885TDP1 4606/4885 |
| US-12049439-B2 | Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives | STS, SULT2A1, SCN2B | ALDH1A1 245/4885KDM4E 3158/4885TDP1 4606/4885 |
| US-12606522-B2 | Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives | NR3C2, NR5A1, SRD5A2 | ALDH1A1 1507/4885KDM4E 3921/4885TDP1 4292/4885 |
| US-20240409508-A1 | SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES | STS, SULT2A1, SCN2B | ALDH1A1 245/4885KDM4E 3158/4885TDP1 4606/4885 |
| US-20120028950-A1 | Substituted heterocyclylbenzylpyrazoles and use thereof | HIF1AN, VHL, HIF1A | ALDH1A1 667/4885KDM4E 2468/4885TDP1 2963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.