Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.36 |
| ▸ | KCNK10 | P57789 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001741 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL19638946 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL695548 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL516309 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL10978325 | 0.75 | ALDH1A1 (0.61) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL513729 | 0.75 | TRPV1 (0.37) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL1745009 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL518851 | 0.73 | ALDH1A1 (0.58) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL7527154 | 0.72 | KIF11 (0.49) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL1020679 | 0.72 | TDP1 (0.47) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230278955-A1 | VITAMIN D3 DERIVATIVES AND PHARMACEUTICAL USE THEREOF | UNIV KYOTO (JP) | 2023-09-07 | — | — | US | disclosed |
| US-20180265463-A1 | Vitamin D3 Derivatives and Pharmaceutical Use Thereof | KYOTO UNIVERSITY (JP) | 2018-09-20 | — | — | US | disclosed |
| EP-3237377-A1 | VITAMIN D3 DERIVATIVES AND PHARMACEUTICAL USE THEREOF | Kyoto University (JP) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016103722-A1 | VITAMIN D3 DERIVATIVES AND PHARMACEUTICAL USE THEREOF | KYOTO UNIVERSITY (JP) | 2016-06-30 | — | — | WO | disclosed |
| CN-102770479-B | Chloro-substituted polyetherimides having improved relative thermal index | SABIC INNOVATIVE PLASTICS IP | 2014-05-21 | — | — | CN | disclosed |
| CN-102595891-B | Amidoacetonitrile compounds having pesticidal activity | NOVARTIS AG | 2013-11-13 | — | — | CN | disclosed |
| CN-102770479-A | Chloro-substituted polyetherimides having improved relative thermal index | SABIC INNOVATIVE PLASTICS IP | 2012-11-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230278955-A1 | VITAMIN D3 DERIVATIVES AND PHARMACEUTICAL USE THEREOF | VDR, CYP24A1, CYP2R1 | ALDH1A1 256/4885KDM4E 1757/4885TDP1 4802/4885 |
| US-20180265463-A1 | Vitamin D3 Derivatives and Pharmaceutical Use Thereof | VDR, CYP24A1, CYP2R1 | ALDH1A1 256/4885KDM4E 1757/4885TDP1 4802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.