SCHEMBL5163345

SCHEMBL5163345

C=C(C[Si](CCCCC)(CCCCC)CCCCC)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37
FNTA P49354 1/20 0.37
FNTB P49356 1/20 0.37
PGGT1B P53609 1/20 0.37
AKR1B1 P15121 1/20 0.37
GPR84 Q9NQS5 7/20 0.35
PPARG P37231 7/20 0.35
PPARD Q03181 7/20 0.35
PPARA Q07869 7/20 0.35
HDAC11 Q96DB2 5/20 0.35
TSHR P16473 4/20 0.35
PTPN1 P18031 3/20 0.35
ALDH1A1 P00352 2/20 0.35
TLR2 O60603 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
FABP4 P15090 2/20 0.35
SLC22A6 Q4U2R8 1/20 0.35
SLC22A8 Q8TCC7 1/20 0.35
MEN1 O00255 1/20 0.35
ESR1 P03372 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5653894 0.94 THRB (0.34) THRBFNTAFNTBPGGT1BAKR1B1
SCHEMBL6884598 0.85 TET2 (0.34) ALOX15HSD17B10
SCHEMBL1729936 0.79 AKR1B1 (0.48) THRBAKR1B1GPR84PPARGPPARD
SCHEMBL5711124 0.72 AKR1B1 (0.44) THRBAKR1B1GPR84PPARGPPARD
SCHEMBL22545 0.72 AKR1B1 (0.56) THRBFNTAFNTBPGGT1BAKR1B1
Heptane SCHEMBL9063841 0.72 THRB (0.48) THRBFNTAFNTBPGGT1BAKR1B1
SCHEMBL6910249 0.72 AKR1B1 (0.56) THRBFNTAFNTBPGGT1BAKR1B1
SCHEMBL5164656 0.71 AKR1B1 (0.39) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL147810 0.70 GPR84 (0.58) THRBFNTAFNTBPGGT1BAKR1B1
SCHEMBL148286 0.70 GPR84 (0.58) THRBFNTAFNTBPGGT1BAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7297727-B2 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. (US) 2007-11-20 US disclosed
EP-1479737-B1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC (US) 2006-08-16 EP disclosed
EP-1479737-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions Atofina Chemicals, Inc. (US) 2004-11-24 EP disclosed
US-20040138332-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. 2004-07-15 US disclosed
US-20030225184-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. 2003-12-04 US disclosed
EP-1367100-A1 Triarylsilyl (meth) acryloyl-containing polymers for marine coating compositions ATOFINA CHEMICALS, INC. (US) 2003-12-03 EP disclosed