SCHEMBL5653894

SCHEMBL5653894

C=C(C[Si](CCCC)(CCCC)CCCC)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.34
FNTA P49354 1/20 0.34
FNTB P49356 1/20 0.34
PGGT1B P53609 1/20 0.34
ALOX15 P16050 2/20 0.33
AKR1B1 P15121 1/20 0.33
TET2 Q6N021 1/20 0.32
GPR84 Q9NQS5 7/20 0.32
PPARG P37231 7/20 0.32
PPARD Q03181 7/20 0.32
PPARA Q07869 7/20 0.32
HDAC11 Q96DB2 5/20 0.32
TSHR P16473 4/20 0.32
PTPN1 P18031 3/20 0.32
ALDH1A1 P00352 2/20 0.32
TLR2 O60603 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
FABP4 P15090 2/20 0.32
SLC22A6 Q4U2R8 1/20 0.32
SLC22A8 Q8TCC7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5163345 0.94 THRB (0.37) THRBFNTAFNTBPGGT1BALOX15
SCHEMBL6884598 0.87 TET2 (0.34) ALOX15TET2HSD17B10
SCHEMBL5711124 0.78 AKR1B1 (0.44) THRBALOX15AKR1B1GPR84PPARG
SCHEMBL1729936 0.71 AKR1B1 (0.48) THRBALOX15AKR1B1GPR84PPARG
SCHEMBL6916130 0.70 CES1 (0.50) THRBFNTAFNTBPGGT1BALOX15
SCHEMBL22623 0.70
SCHEMBL4832778 0.70 AKR1B1 (0.36) ALOX15AKR1B1GPR84PPARGPPARD
SCHEMBL4919090 0.69 TET2 (0.31) TET2
SCHEMBL2578200 0.69 CES1 (0.48) THRBFNTAFNTBPGGT1BALOX15
SCHEMBL6910249 0.69 AKR1B1 (0.56) THRBFNTAFNTBPGGT1BALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1310530-B1 COATING COMPOSITIONS ARKEMA INC (US) 2016-01-06 EP disclosed
EP-1342756-B2 Antifouling coating composition, coating film therefrom, underwater material covered with the coating film and antifouling method CHUGOKU MARINE PAINTS (JP) 2015-06-24 EP disclosed
EP-1342756-B1 Antifouling coating composition, coating film therefrom, underwater material covered with the coating film and antifouling method CHUGOKU MARINE PAINTS (JP) 2006-11-15 EP disclosed
US-6992120-B2 Coating compositions ARKEMA INC. (US) 2006-01-31 US disclosed
US-20040236130-A1 Process for the preparation of trialkylsilated carboxylate monomers, the obatined trialkylsilated carboxylate monomers and their use in anti-fouling coatings SIGMA COATINGS B.V. (NL) 2004-11-25 US disclosed
EP-1263898-B1 IMPROVED MARINE PAINT COMPOSITIONS SIGMA COATINGS BV (NL) 2004-09-22 EP disclosed
US-6710117-B2 PAINT THAT HYDROLYSES AT A PREDETERMINED RATE IN THE PRESENCE OF SEA WATER SIGMA COATINGS B.V. (NL) 2004-03-23 US disclosed
EP-1389214-A1 PROCESS FOR THE PREPARATION OF TRIALKYLSILYLATED CARBOXYLATE MONOMERS, THE OBTAINED TRIALKYLSILYLATED CARBOXYLATE MONOMERS AND THEIR USE IN ANTI-FOULING COATINGS SIGMA COATINGS B.V. (NL) 2004-02-18 EP disclosed
US-20030166768-A1 Marine paint compositions SYNPHORA AB (SE) 2003-09-04 US disclosed
US-20030162924-A1 Metal-free binders for self-polishing antifouling paints SIGMA COATINGS B.V. (NL) 2003-08-28 US disclosed
US-20030109597-A1 Copolymers containing trialkylsilylacrylate units are erodible in seawater and can be used to formulate antifouling marine paints. The copolymers are characterized by low levels of silylacrylate component in amounts ranging from 30 to 80 ARKEMA INC. 2003-06-12 US disclosed
EP-1310530-A1 Coating compositions Atofina Chemicals, Inc. (US) 2003-05-14 EP disclosed
EP-1263898-A1 IMPROVED MARINE PAINT COMPOSITIONS SIGMA COATINGS B.V. (NL) 2002-12-11 EP disclosed
WO-2002094838-A1 PROCESS FOR THE PREPARATION OF TRIALKYLSILYLATED CARBOXYLATE MONOMERS, THE OBTAINED TRIALKYLSILYLATED CARBOXYLATE MONOMERS AND THEIR USE IN ANTI-FOULING COATINGS SIGMA COATINGS B.V. (NL) 2002-11-28 WO disclosed
EP-1260513-A1 Process for the preparation of trialkylsilylated carboxylate monomers, the obtained trialkylsilylated carboxylate monomers and their use in antifouling coatings SIGMA COATINGS B.V. (NL) 2002-11-27 EP disclosed
WO-2001062858-A1 IMPROVED MARINE PAINT COMPOSITIONS SIGMA COATINGS B.V. (NL) 2001-08-30 WO disclosed
EP-1127902-A1 Metal-free binders for self-polishing anti-fouling paints SIGMA COATINGS B.V. (NL) 2001-08-29 EP disclosed
EP-1127925-A1 Marine paint compositions SIGMA COATINGS B.V. (NL) 2001-08-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040236130-A1 Process for the preparation of trialkylsilated carboxylate monomers, the obatined trialkylsilated carboxylate monomers and their use in anti-fouling coatings ACMSD, OR10J3, CFD THRB 2910/4885FNTA 2997/4885FNTB 2916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.