Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5158724 | 0.77 | LMNA (0.43) | — | |
| SCHEMBL5158618 | 0.77 | GPR84 (0.33) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL5160371 | 0.76 | FAAH (0.45) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL5160652 | 0.76 | GPR84 (0.37) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL5160702 | 0.75 | TRPA1 (0.40) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL5163156 | 0.74 | GPR84 (0.33) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL5158441 | 0.74 | PIK3CD (0.40) | PIK3CDPTGS2 | |
| SCHEMBL3033757 | 0.73 | GPR84 (0.52) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL5162442 | 0.73 | EGLN1 (0.39) | — | |
| SCHEMBL5162482 | 0.73 | NPC1 (0.35) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1340746-B1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | SALTIGO GMBH (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1340746-A1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | BAYER AG (DE) | 2003-09-03 | — | — | EP | disclosed |