SCHEMBL516386

SCHEMBL516386

CC(=O)C(CCC(=O)O)C(C)=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 5/20 0.50
GABRP O00591 2/20 0.50
GABRD O14764 2/20 0.50
GABRA1 P14867 2/20 0.50
GABRB1 P18505 2/20 0.50
GABRG2 P18507 2/20 0.50
GABRB3 P28472 2/20 0.50
GABRA5 P31644 2/20 0.50
GABRA3 P34903 2/20 0.50
GABRA2 P47869 2/20 0.50
GABRB2 P47870 2/20 0.50
GABRA4 P48169 2/20 0.50
GABRE P78334 2/20 0.50
GABRA6 Q16445 2/20 0.50
GABRG1 Q8N1C3 2/20 0.50
GABRG3 Q99928 2/20 0.50
GABRQ Q9UN88 2/20 0.50
CYP1A2 P05177 2/20 0.50
TET2 Q6N021 3/20 0.46
KDM4A O75164 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7000281 0.92 CYP1A2 (0.54) FOLH1GABRPGABRDGABRA1GABRB1
SCHEMBL9482708 0.85 FOLH1 (0.43) FOLH1GABRPGABRDGABRA1GABRB1
SCHEMBL6088956 0.84 LMNA (0.48) LMNAENPEPNFKB1
Succinic Acid SCHEMBL30420635 0.82 LMNA (0.46) LMNASLC15A2ALKBH5SUCNR1EGLN1
SCHEMBL6259052 0.80 GABRP (0.43) FOLH1GABRPGABRDGABRA1GABRB1
SCHEMBL1406339 0.80 ALDH1A1 (0.50) FOLH1LMNASLC15A2
SCHEMBL669817 0.79 FOLH1 (0.64) FOLH1GABRPGABRDGABRA1GABRB1
SCHEMBL28576168 0.79 GABRP (0.42) FOLH1GABRPGABRDGABRA1GABRB1
SCHEMBL10533971 0.78 FOLH1 (0.54) FOLH1GABRPGABRDGABRA1GABRB1
SCHEMBL79512 0.77 LMNA (0.46) FOLH1CYP1A2TET2KDM4AKDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116970746-B Synthetic tanning agent containing hexabasic carbonyl and preparation method and application thereof 南京工业大学 2025-03-18 CN disclosed
US-20240390364-A1 Novel Pyridine Compositions and their use in methods for preventing or treating diseases, disorders and conditions REID CHRISTOPHER BRIAN (US) 2024-11-28 US disclosed
CN-118084638-A Continuous production method and device of 1, 3-cyclohexanedione 宁波天研精开技术有限公司 2024-05-28 CN disclosed
US-11988809-B2 Laminate, antireflection product, and manufacturing method thereof FUJIFILM CORPORATION (JP) 2024-05-21 US disclosed
CN-116219085-B Synthetic tanning agent containing multifunctional structure and preparation method and application thereof 南京工业大学 2024-03-15 CN disclosed
CN-116970746-A Synthetic tanning agent containing hexabasic carbonyl and preparation method and application thereof 南京工业大学 2023-10-31 CN disclosed
CN-116219085-A Synthetic tanning agent containing multifunctional structure and preparation method and application thereof 南京工业大学 2023-06-06 CN disclosed
US-11209575-B2 Laminate, antireflection product, and manufacturing method thereof FUJIFILM CORPORATION (JP) 2021-12-28 US disclosed
EP-3150203-B1 COMPOUNDS WITH (1E,6E)-1,7-BIS-(3,4- DIMETHOXYPHENYL)-4,4-DISSTITUTED-HEPA-1,6-DIENE-3,5-DI-ONE STRUCTURAL SCAFFOLD,THEIR BIOLOGICAL ACTIVITY, AND USES THEREOF ALLIANZ PHARMASCIENCE LTD (TW) 2020-02-19 EP disclosed
US-10561650-B2 Method for treating a protozoal infection REID CHRISTOPHER BRIAN (US) 2020-02-18 US disclosed
US-20030113666-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2003-06-19 US disclosed
EP-1302313-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2003-04-16 EP disclosed
US-6197071-B1 HAIR DYES; LIGHT STABILITY; COLOR PHOTOGRAPHY EASTMAN KODAK COMPANY 2001-03-06 US disclosed
US-6140033-A SUPPORT WITH SILVER HALIDE EMULSIONS WITH COUPLERS EASTMAN KODAK COMPANY (US) 2000-10-31 US disclosed
EP-1014185-A1 Photographic element, pyrazolazole coupler, method for it's preparation and an azomethine dye EASTMAN KODAK COMPANY (US) 2000-06-28 EP disclosed
US-5252603-A Immunosuppressive analogues and derivatives of succinylacetone CETUS CORPORATION (US) 1993-10-12 US disclosed
US-5216005-A Treating autoimmune diseases, organ tissue transplants CETUS CORPORATION (US) 1993-06-01 US disclosed
US-5173482-A A dioxoalkyl phosponate or a proline-modified polyoxyethylene glycol derivative; autoimmune diseases; organ transplants; immunoassay CETUS CORPORATION (US) 1992-12-22 US disclosed
US-4895872-A TREATING HYPERACTIVE IMMUNE SYSTEMS; AUTOIMMUNE AND GRAFT/HOST DISEASES CETUS CORPORATION (US) 1990-01-23 US disclosed
WO-1990000049-A2 IMMUNOSUPPRESSIVE ANALOGUES AND DERIVATIVES OF SUCCINYLACETONE CETUS CORPORATION (US) 1990-01-11 WO disclosed