Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.43 |
| ▸ | GABRD | O14764 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.43 |
| ▸ | GABRE | P78334 | 2/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2818593 | 0.90 | GABRP (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11124032 | 0.87 | FFAR4 (0.44) | TDP1ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL3762538 | 0.86 | ALDH1A1 (0.41) | TDP1ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL1201909 | 0.84 | L3MBTL1 (0.51) | TDP1ALDH1A1LMNAHSD17B10CYP1A2 | |
| SCHEMBL3010250 | 0.81 | ALDH1A1 (0.44) | TDP1ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL28576166 | 0.81 | L3MBTL1 (0.45) | TDP1ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL516386 | 0.80 | FOLH1 (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL482827 | 0.79 | TDP1 (0.46) | TDP1ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL1406252 | 0.79 | ALDH1A1 (0.42) | TDP1ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL6664974 | 0.78 | L3MBTL1 (0.39) | TDP1ALDH1A1LMNAHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810044-A | A kind of compound and its preparation and application with HIV-1 integrase inhibiting activities | 贵州医科大学 | 2019-05-28 | — | — | CN | claimed |
| CN-109810044-A | A kind of compound and its preparation and application with HIV-1 integrase inhibiting activities | 贵州医科大学 | 2019-05-28 | — | — | CN | disclosed |
| CN-100384889-C | Polymerization of olefins | DU PONT (US) | 2008-04-30 | — | — | CN | disclosed |
| CN-100372851-C | Fused pyrimidine derivatives with CRF activity | HOFFMANN LA ROCHE (CH) | 2008-03-05 | — | — | CN | disclosed |
| CN-1784409-A | Fused pyrimidine derivatives with CRF activity | HOFFMANN LA ROCHE (CH) | 2006-06-07 | — | — | CN | disclosed |
| EP-1085016-B1 | HETEROCYCLE-BEARING THIO PHENOL COMPOUNDS, INTERMEDIATES FOR THE PREPARATION OF THE SAME AND PROCESSES FOR THE PREPARATION OF BOTH | NIPPON SODA CO (JP) | 2005-11-02 | — | — | EP | disclosed |
| CN-1199963-C | Coumarin derivatives with COMT inhibiting activity | ORION CORP (FI) | 2005-05-04 | — | — | CN | disclosed |
| CN-1440399-A | Coumarin derivatives with COMT inhibiting activity | ORION CORP (FI) | 2003-09-03 | — | — | CN | disclosed |
| CN-1115337-C | Pyrimidinone derivs. | BORYUNG PHARM (KR) | 2003-07-23 | — | — | CN | disclosed |
| US-6359143-B1 | CHEMICAL INTERMEDIATE; HERBICIDES | NIPPON SODA CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-1085016-A1 | HETEROCYCLE-BEARING THIO PHENOL COMPOUNDS, INTERMEDIATES FOR THE PREPARATION OF THE SAME AND PROCESSES FOR THE PREPARATION OF BOTH | NIPPON SODA CO., LTD. (JP) | 2001-03-21 | — | — | EP | disclosed |
| CN-1243519-A | Olefin polymerization | DU PONT (US) | 2000-02-02 | — | — | CN | disclosed |
| CN-1160395-A | Pyrimidone derivatives | BORYUNG PHARM (KR) | 1997-09-24 | — | — | CN | disclosed |
| US-5358989-A | Compositions of polyphenylene oxide or mixtures of polyphenylene oxide with β-diketones | ENICHEM S.P.A. (IT) | 1994-10-25 | — | — | US | disclosed |
| US-5194476-A | And blends of homo- or copolymers of styrene; heat resistance, fluidity; medical equipment, electronics | ECP ENICHEM POLIMERI S.R.L. (IT) | 1993-03-16 | — | — | US | disclosed |
| EP-0480383-A2 | Polyphenylene oxide compositions stabilized with beta-diketones | ENICHEM S.p.A. (IT) | 1992-04-15 | — | — | EP | disclosed |
| US-4480106-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, LIGHT STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |