Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164333 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EMEN1TP53 | |
| SCHEMBL5163331 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EMEN1TP53 | |
| SCHEMBL5163324 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EMEN1TP53 | |
| SCHEMBL5163385 | 0.72 | TTR (0.43) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7534360 | 0.70 | TNFSF11 (0.47) | ALDH1A1MAPTKDM4EMEN1TP53 | |
| SCHEMBL7534362 | 0.70 | TNFSF11 (0.47) | ALDH1A1MAPTKDM4EMEN1TP53 | |
| SCHEMBL23591532 | 0.69 | KDM4E (0.57) | ALDH1A1MAPTKDM4EMEN1TP53 | |
| SCHEMBL30453685 | 0.67 | KDM4E (0.46) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL336624 | 0.67 | KDM4E (0.46) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL1823414 | 0.67 | FDPS (0.43) | ALDH1A1MAPTKDM4EMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758850-A1 | PREPARATION AND APPLICATIONS OF POLYMER-SUPPORTED HALOGENATED BENZOQUINONES AS OXIDATIVE AGENTS | COULADOUROS, Elias, Andrea (GR) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005121077-A1 | PREPARATION AND APPLICATIONS OF POLYMER-SUPPORTED HALOGENATED BENZOQUINONES AS OXIDATIVE AGENTS | COULADOUROS ELIAS (GR) | 2005-12-22 | — | — | WO | disclosed |