Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | LDHB | P07195 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30453685 | 0.75 | KDM4E (0.46) | CFDMAOBTNFSF11KDM4EALDH1A1 | |
| SCHEMBL336624 | 0.75 | KDM4E (0.46) | CFDMAOBTNFSF11KDM4EALDH1A1 | |
| SCHEMBL13865018 | 0.74 | LDHA (0.38) | LDHALDHBAKR1B1CFDMAOB | |
| SCHEMBL5164338 | 0.72 | ALDH1A1 (0.42) | TTRLDHALDHBAKR1B1APP | |
| SCHEMBL5164333 | 0.72 | ALDH1A1 (0.42) | TTRLDHALDHBAKR1B1APP | |
| Acetic Acid SCHEMBL336195 | 0.72 | KDM4E (0.47) | CFDMAOBKDM4EALDH1A1GAA | |
| SCHEMBL5163600 | 0.71 | PIM1 (0.47) | LDHALDHBAKR1B1CFDMAOB | |
| SCHEMBL8773709 | 0.69 | CYP3A4 (0.48) | TTRKDM4EALDH1A1PTGS2MEN1 | |
| SCHEMBL15766152 | 0.68 | CFD (0.42) | CFDMAOBKDM4EALDH1A1GAA | |
| SCHEMBL10048512 | 0.68 | TNFSF11 (0.38) | LDHALDHBAKR1B1CFDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758850-A1 | PREPARATION AND APPLICATIONS OF POLYMER-SUPPORTED HALOGENATED BENZOQUINONES AS OXIDATIVE AGENTS | COULADOUROS, Elias, Andrea (GR) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005121077-A1 | PREPARATION AND APPLICATIONS OF POLYMER-SUPPORTED HALOGENATED BENZOQUINONES AS OXIDATIVE AGENTS | COULADOUROS ELIAS (GR) | 2005-12-22 | — | — | WO | disclosed |