SCHEMBL5166207

SCHEMBL5166207

OCCOB(O)c1ccccc1F

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
RECQL P46063 1/20 0.35
CYP1A2 P05177 1/20 0.32
ENPP2 Q13822 1/20 0.31
NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5953023 0.89 PTPN1 (0.31) CYP1A2
SCHEMBL1760270 0.78 ALDH1A1 (0.38) ALDH1A1RECQLCYP1A2ENPP2
SCHEMBL5953133 0.75 HTR1B (0.40) ALDH1A1RECQLCYP1A2
SCHEMBL16232296 0.74 NFE2L2 (0.36) ALDH1A1ENPP2NFE2L2
SCHEMBL16247936 0.74 ENPP2 (0.45) ENPP2NFE2L2
SCHEMBL1138569 0.74 ESR2 (0.35) ALDH1A1RECQL
SCHEMBL4584090 0.73 LIPE (0.35) ALDH1A1RECQLENPP2
Fluorobenzene SCHEMBL10445356 0.73 ENPP2 (0.40) ALDH1A1RECQLCYP1A2ENPP2
SCHEMBL8611704 0.73 FOLH1 (0.38) ALDH1A1RECQL
SCHEMBL117263 0.72 ALDH1A1 (0.45) ALDH1A1RECQLCYP1A2ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1765359-A2 ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE Anacor Pharmaceuticals, Inc. (US) 2007-03-28 EP disclosed
WO-2006007384-A2 ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE ANACOR PHARMACEUTICALS, INC. (US) 2006-01-19 WO disclosed