Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3098282 | 0.99 | ALDH1A1 (0.50) | ALDH1A1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL5166952 | 0.87 | HRH3 (0.55) | ALDH1A1OPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL3085793 | 0.86 | HRH3 (0.54) | ALDH1A1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL3081018 | 0.84 | ALDH1A1 (0.60) | ALDH1A1KMT2AOPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL11194779 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL5168106 | 0.82 | OPRM1 (0.60) | ALDH1A1KMT2AOPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL3092573 | 0.81 | OPRM1 (0.58) | ALDH1A1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL17848367 | 0.81 | MEN1 (0.58) | ALDH1A1KMT2AOPRL1MEN1LMNA | |
| SCHEMBL5166771 | 0.80 | ALDH1A1 (0.60) | ALDH1A1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL5165555 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KMT2AOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771417-A1 | SUBSTITUTED 3-PHENYLPIPERIDINE DERIVATIVES | Grünenthal GmbH (DE) | 2007-04-11 | — | — | EP | claimed |
| WO-2006010577-A1 | SUBSTITUTED 3-PHENYLPIPERIDINE DERIVATIVES | Grünenthal GmbH (DE) | 2006-02-02 | — | — | WO | claimed |
| EP-1771417-A1 | SUBSTITUTED 3-PHENYLPIPERIDINE DERIVATIVES | Grünenthal GmbH (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010577-A1 | SUBSTITUTED 3-PHENYLPIPERIDINE DERIVATIVES | Grünenthal GmbH (DE) | 2006-02-02 | — | — | WO | disclosed |