Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165572 | 0.77 | TAAR1 (0.37) | TAAR1HSD17B10MEN1ALDH1A1MAPT | |
| SCHEMBL5165290 | 0.77 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL386428 | 0.75 | IRAK4 (0.31) | ALDH1A1 | |
| SCHEMBL384900 | 0.75 | FPR2 (0.39) | FPR2HSD17B10MEN1ALDH1A1MAPT | |
| SCHEMBL7614673 | 0.74 | FPR2 (0.39) | TAAR1FPR2MEN1ALDH1A1MAPT | |
| SCHEMBL7615636 | 0.73 | S1PR1 (0.42) | TAAR1FPR2HSD17B10ALDH1A1MAPT | |
| SCHEMBL385654 | 0.73 | RAB9A (0.35) | MEN1ALDH1A1MAPTKMT2AHSD11B1 | |
| SCHEMBL5170413 | 0.72 | HCAR3 (0.30) | — | |
| SCHEMBL385579 | 0.72 | S1PR1 (0.30) | — | |
| SCHEMBL4462359 | 0.72 | S1PR1 (0.33) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300405-B1 | AMINO ALCOHOL DERIVATIVES | SANKYO CO (JP) | 2007-04-18 | — | — | EP | disclosed |
| EP-1300405-A1 | AMINO ALCOHOL DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-09 | — | — | EP | disclosed |