Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 1.00 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 1.00 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.65 |
| ▸ | NOD1 | Q9Y239 | 7/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutathione SCHEMBL28505216 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Glutathione SCHEMBL14364095 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Glutathione SCHEMBL272141 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Glutathione SCHEMBL5167025 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Glutathione SCHEMBL5167030 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Glutathione SCHEMBL13105609 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Glutathione SCHEMBL7469803 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Glutathione SCHEMBL9167 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Glutathione SCHEMBL15701576 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Glutathione SCHEMBL30733475 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382946-A1 | POLYPEPTIDE OR PROTEIN DIRECTIONAL MODIFICATION METHOD BASED ON SULFHYDRYL-ALKENYL AZIDE COUPLING | Changzhou University (CN) | 2023-11-30 | — | — | US | disclosed |
| US-11534475-B2 | Carbohydrate-based peritoneal dialysis fluid comprising glutamine residue | ZYTOPROTEC GMBH (AT) | 2022-12-27 | — | — | US | disclosed |
| CN-114317647-A | Method for producing glutathione by using genetic engineering escherichia coli | 无锡福祈制药有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-109709182-B | Based on g-C3N4-MnO2Method for ultrasensitive detection of glutathione by photo-electrochemical method of nano composite material | 济南大学 | 2021-03-26 | — | — | CN | disclosed |
| US-20200281235-A1 | METHOD FOR MANUFACTURING SEASONING | MITSUBISHI CORPORATION LIFE SCIENCES LIMITED (JP) | 2020-09-10 | — | — | US | disclosed |
| CN-105712964-B | Preparation method and application of thiol fluorescent probe based on coumaroyl hydrazide | 新乡医学院 | 2020-07-07 | — | — | CN | disclosed |
| US-10688122-B2 | Thiol and disulfide-containing agents for increasing meibomian gland lipid secretion | Azura Ophthalmics Ltd. (IL) | 2020-06-23 | — | — | US | disclosed |
| US-20200113965-A1 | CARBOHYDRATE-BASED PERITONEAL DIALYSIS FLUID COMPRISING GLUTAMINE RESIDUE | ZYTOPROTEC GMBH (AT) | 2020-04-16 | — | — | US | disclosed |
| CN-109709182-A | A kind of g-C3N4-MnO2The photic electrochemical process super sensitivity detection glutathione of nanocomposite | 济南大学 | 2019-05-03 | — | — | CN | disclosed |
| EP-2129370-A1 | CARBOHYDRATE-BASED PERITONEAL DIALYSIS FLUID COMPRISING GLUTAMINE RESIDUE | Zytoprotec Gmbh (AT) | 2009-12-09 | — | — | EP | disclosed |
| US-20080255226-A1 | STABILIZED ANTHOCYANIN COMPOSITIONS | OMNICA GMBH (DE) | 2008-10-16 | — | — | US | disclosed |
| WO-2008106702-A1 | CARBOHYDRATE-BASED PERITONEAL DIALYSIS FLUID COMPRISING GLUTAMINE RESIDUE | ZYTOPROTEC GMBH (AT) | 2008-09-12 | — | — | WO | disclosed |
| WO-2008066816-A2 | DERIVATIZATION OR LIGATON OF PEPTIDES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-06-05 | — | — | WO | disclosed |
| US-20070148712-A1 | Breast cancer and prostate cancer assessment | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2007-06-28 | — | — | US | disclosed |
| WO-2006133408-A9 | BREAST CANCER AND PROSTATE CANCER ASSESSMENT | UNIV IOWA STATE RES FOUND INC (US) | 2007-04-12 | — | — | WO | disclosed |
| WO-2006133408-A2 | BREAST CANCER AND PROSTATE CANCER ASSESSMENT | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | WO | disclosed |
| EP-0300168-B1 | PROCESS FOR THE GLUTATHIONE SYNTHESIS IN YEAST | HÜLS AKTIENGESELLSCHAFT (DE) | 1993-01-13 | — | — | EP | disclosed |
| EP-0300168-A2 | Process for the glutathione synthesis in yeast | HÜLS AKTIENGESELLSCHAFT (DE) | 1989-01-25 | — | — | EP | disclosed |
| EP-0300168-A2 | Process for the glutathione synthesis in yeast | HÜLS AKTIENGESELLSCHAFT (DE) | 1989-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10688122-B2 | Thiol and disulfide-containing agents for increasing meibomian gland lipid secretion | TXN, MGST3, MGST1 | PTGS1 227/4885GSTK1 31/4885GLO1 201/4885 |
| US-20080255226-A1 | STABILIZED ANTHOCYANIN COMPOSITIONS | NQO1, CRY2, GANC | PTGS1 2891/4885GSTK1 2995/4885GLO1 474/4885 |
| US-20230382946-A1 | POLYPEPTIDE OR PROTEIN DIRECTIONAL MODIFICATION METHOD BASED ON SULFHYDRYL-ALKENYL AZIDE COUPLING | PTMS, CBS, CHAMP1 | PTGS1 2134/4885GSTK1 496/4885GLO1 519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.