Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 1.00 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 1.00 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.65 |
| ▸ | NOD1 | Q9Y239 | 7/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutathione SCHEMBL28505216 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Glutathione SCHEMBL14364095 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Glutathione SCHEMBL272141 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Glutathione SCHEMBL5167025 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Glutathione SCHEMBL5167030 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Glutathione SCHEMBL13105609 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Glutathione SCHEMBL9167 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Glutathione SCHEMBL15701576 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Glutathione SCHEMBL1105665 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 | |
| Glutathione SCHEMBL30733475 | 1.00 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240156826-A1 | METHODS OF TREATING LIVER DISORDERS OR LIPID DISORDERS WITH A THR-BETA AGONIST | LSI FINANCING LLC, AS ADMINISTRATIVE AGENT | 2024-05-16 | — | — | US | disclosed |
| CN-117871699-A | Application of group of markers in detection of oxaliplatin adverse reaction | 李鸿雁 | 2024-04-12 | — | — | CN | disclosed |
| WO-2023223223-A1 | A PHARMACEUTICAL COMPOSITION FOR USE IN PREVENTING AND/OR REDUCING HEPATOTOXICITY INDUCED BY ACETAMINOPHEN | APTYS PHARMACEUTICALS SAS (FR) | 2023-11-23 | — | — | WO | disclosed |
| US-11806353-B2 | Methods of treating liver disorders or lipid disorders with a THR-beta agonist | MADRIGAL PHARMACEUTICALS, INC. (US) | 2023-11-07 | — | — | US | disclosed |
| EP-4112056-A1 | METHODS OF TREATING LIVER DISORDERS OR LIPID DISORDERS WITH A THR-BETA AGONIST | Madrigal Pharmaceuticals, Inc. (US) | 2023-01-04 | — | — | EP | disclosed |
| WO-2018089481-A1 | MITOMYCIN C PRODRUG LIPOSOME FORMULATIONS AND USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-17 | — | — | WO | disclosed |
| US-20140121100-A1 | COMPOSITIONS AND METHODS FOR ENHANCING PLANT GROWTH | NOVOZYMES BIOAG A/S (DK) | 2014-05-01 | — | — | US | disclosed |
| CN-102103141-B | Immunity-chromatography kit for rapid diagnosis of malaria and its pathogen species and preparation method thereof | NAT INST OF PARASITIC DISEASE CHINESE CT FOR DISEASE CONTROL AND PREVENTION | 2014-04-09 | — | — | CN | disclosed |
| CN-102103141-A | Immunity-chromatography kit for rapid diagnosis of malaria and its pathogen species and preparation method thereof | NAT INST OF PARASITIC DISEASE CHINESE CT FOR DISEASE CONTROL AND PREVENTION | 2011-06-22 | — | — | CN | disclosed |
| US-20070269375-A1 | Stable Radiopharmaceutical Compositions and Methods for Preparation | BRACCO IMAGING S.P.A. (IT) | 2007-11-22 | — | — | US | disclosed |
| WO-2002029103-A2 | GENE EXPRESSION PROFILES IN LIVER CANCER | GENE LOGIC, INC. (US) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240156826-A1 | METHODS OF TREATING LIVER DISORDERS OR LIPID DISORDERS WITH A THR-BETA AGONIST | THRB, THRA, CPT1A | PTGS1 1854/4885GSTK1 791/4885GLO1 1246/4885 |
| US-20070269375-A1 | Stable Radiopharmaceutical Compositions and Methods for Preparation | GRPR, GIPR, SSTR3 | PTGS1 4001/4885GSTK1 3661/4885GLO1 2938/4885 |
| US-11806353-B2 | Methods of treating liver disorders or lipid disorders with a THR-beta agonist | THRB, THRA, CPT1A | PTGS1 1854/4885GSTK1 791/4885GLO1 1246/4885 |
| US-20140121100-A1 | COMPOSITIONS AND METHODS FOR ENHANCING PLANT GROWTH | GSS, GSTO1, GSTA1 | PTGS1 111/4885GSTK1 23/4885GLO1 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.