Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4163022 | 0.72 | SPR (0.46) | HPGDALDH1A1LMNAKDM4EGAA | |
| SCHEMBL5166818 | 0.71 | MMP1 (0.46) | HPGDALDH1A1LMNAKDM4EGAA | |
| SCHEMBL12677941 | 0.69 | HPGD (0.45) | HPGDALDH1A1LMNAKDM4EGAA | |
| SCHEMBL2540575 | 0.69 | POLB (0.43) | ALDH1A1KDM4EGAAHSD17B10KMT2A | |
| SCHEMBL12086278 | 0.66 | BAZ2B (0.54) | HPGDALDH1A1LMNAKDM4EGAA | |
| SCHEMBL13295979 | 0.65 | ALDH1A1 (0.46) | HPGDALDH1A1LMNAKDM4EGAA | |
| SCHEMBL2568515 | 0.64 | APOBEC3A (0.42) | HPGDALDH1A1LMNAKDM4EGAA | |
| SCHEMBL32690490 | 0.64 | POLB (0.36) | ALDH1A1KMT2APOLB | |
| SCHEMBL12424182 | 0.63 | APOBEC3A (0.49) | HPGDALDH1A1LMNAKDM4EGAA | |
| SCHEMBL11559372 | 0.62 | POLB (0.43) | ALDH1A1LMNAKDM4EGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440061-B1 | PROCESSES FOR THE MANUFACTURING OF 3-HYDROXY-N,1,6-TRIALKYL-4-OXO-1,4-DIHYDROPYRIDINE-2-CARBOXAMIDE | APOTEX INC (CA) | 2007-04-11 | — | — | EP | disclosed |
| EP-1440061-A1 | PROCESSES FOR THE MANUFACTURING OF 3-HYDROXY-N,1,6-TRIALKYL-4-OXO-1,4-DIHYDROPYRIDINE-2-CARBOXAMIDE | APOTEX INC. (CA) | 2004-07-28 | — | — | EP | disclosed |
| WO-2003037867-A1 | PROCESSES FOR THE MANUFACTURING OF 3-HYDROXY-N,1,6-TRIALKYL-4-OXO-1,4-DIHYDROPYRIDINE-2-CARBOXAMIDE | APOTEX INC. (CA) | 2003-05-08 | — | — | WO | disclosed |