Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164598 | 0.89 | PTGS2 (0.60) | GABRA1GABRB2PTGS2CYP3A4CNR1 | |
| SCHEMBL9849323 | 0.88 | GABRA1 (0.48) | GABRA1GABRB2PTGS2CYP3A4PTPN1 | |
| SCHEMBL1033820 | 0.85 | GABRA1 (0.44) | GABRA1GABRB2PTGS2CYP3A4CNR1 | |
| SCHEMBL9935963 | 0.85 | HTR1D (0.40) | GABRA1GABRB2PTGS2CYP3A4CNR1 | |
| SCHEMBL5167852 | 0.83 | GABRA1 (0.62) | GABRA1GABRB2PTGS2CYP3A4LTA4H | |
| SCHEMBL67909 | 0.80 | PTGS2 (0.70) | PTGS2CYP3A4PTPN1PTPN11CNR1 | |
| SCHEMBL3362484 | 0.80 | PTGS2 (0.62) | PTGS2CYP3A4PTPN1PTPN11CNR1 | |
| SCHEMBL17341731 | 0.79 | PTGS2 (0.44) | GABRA1GABRB2PTGS2CYP3A4PTPN1 | |
| SCHEMBL12115600 | 0.79 | GABRA1 (0.62) | GABRA1GABRB2PTGS2CYP3A4GPR84 | |
| SCHEMBL3811969 | 0.78 | RXRA (0.58) | GABRA1GABRB2CYP3A4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101817713-B | Preparation method of 2, 2'-biphenyl diphenol and derivatives thereof | BEIJING OKEANOS TECHNOLOGY CO LTD | 2013-06-12 | — | — | CN | disclosed |
| CN-101817713-A | Preparation method of 2, 2'-biphenyl diphenol and derivatives thereof | BEIJING OKEANOS TECHNOLOGY CO LTD | 2010-09-01 | — | — | CN | disclosed |
| US-20070129578-A1 | Method for the production of 2,2'-dihydroxybiphenyls | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-07 | — | — | US | disclosed |
| EP-1633691-B1 | METHOD FOR PRODUCING 2,2'-DIHYDROXY-BIPHENYLS | BASF AG (DE) | 2007-04-11 | — | — | EP | disclosed |
| EP-1682473-A1 | METHOD FOR THE PRODUCTION OF 2,2'-DIHYDROXYBIPHENYLS | BASF Aktiengesellschaft (DE) | 2006-07-26 | — | — | EP | disclosed |
| CN-1802339-A | Method for producing 2,2'-dihydroxy-biphenyls | BASF AG (DE) | 2006-07-12 | — | — | CN | disclosed |
| EP-1633691-A1 | METHOD FOR PRODUCING 2,2'-DIHYDROXY-BIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2006-03-15 | — | — | EP | disclosed |
| WO-2005042454-A1 | METHOD FOR THE PRODUCTION OF 2,2'-DIHYDROXYBIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-12 | — | — | WO | disclosed |
| WO-2004108642-A1 | METHOD FOR PRODUCING 2,2'-DIHYDROXY-BIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2004-12-16 | — | — | WO | disclosed |
| WO-2004069779-A1 | METHOD FOR PRODUCING 2,2'-DIHYDROXYBIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-19 | — | — | WO | disclosed |
| EP-0445827-B1 | 4-Hydroxytetrahydropyran-2-one derivatives useful as cholesterol and lipid reducing agents | FUJIREBIO KK (JP) | 1996-09-25 | — | — | EP | disclosed |
| US-5149834-A | Anticholesterol agent and enzyme inhibitors, for curing arteriosclerosis | FUJIREBIO INC. (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0445827-A2 | 4-Hydroxytetrahydropyran-2-one derivatives useful as cholesterol and lipid reducing agents | FUJIREBIO INC. (JP) | 1991-09-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129578-A1 | Method for the production of 2,2'-dihydroxybiphenyls | HAO2, DAO, DDO | GABRA1 1782/4885GABRB2 1341/4885PTGS2 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.