SCHEMBL5167622

SCHEMBL5167622

COC(OC)c1c(F)c(F)cc(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 1/20 0.31
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA4 P22748 1/20 0.30
CA12 O43570 1/20 0.30
CA7 P43166 1/20 0.30
CA13 Q8N1Q1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8573158 0.78
SCHEMBL6769767 0.76 CA1 (0.32) CA1CA2CA4CA12CA7
SCHEMBL5167373 0.75 THRB (0.31)
SCHEMBL5165575 0.71
SCHEMBL19713405 0.71
SCHEMBL9003976 0.70 CA1 (0.33) CA1CA2CA4CA12CA7
Methoxymethane SCHEMBL27756535 0.69 CA1 (0.36) TUBB1CA1CA2CA4CA12
SCHEMBL19734467 0.69 PTGS2 (0.38)
SCHEMBL16103807 0.69 ACHE (0.30)
SCHEMBL16740710 0.67 ALDH1A1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1182184-B1 PROCESS FOR PRODUCING TETRAFLUORO BENZENECARBALDEHYDES AND TETRAFLUORO BENZENEMETHANOLS SHOWA DENKO KK (JP) 2007-04-18 EP claimed
CN-1237037-C Process for producing tetrafluoro benzenemethanols SHOWA DENKO KK (JP) 2006-01-18 CN claimed
CN-115259996-B Synthesis method of 2,3,5, 6-tetrafluorobenzyl alcohol 浙江中欣氟材股份有限公司 2024-02-02 CN disclosed
CN-115259996-A Synthetic method of transfluthrin intermediate 浙江中欣氟材股份有限公司 2022-11-01 CN disclosed
CN-113292399-B Synthetic method of transfluthrin intermediate 浙江中欣氟材股份有限公司 2021-11-26 CN disclosed
CN-113292399-A Synthetic method of transfluthrin intermediate 浙江中欣氟材股份有限公司 2021-08-24 CN disclosed
EP-1182184-B1 PROCESS FOR PRODUCING TETRAFLUORO BENZENECARBALDEHYDES AND TETRAFLUORO BENZENEMETHANOLS SHOWA DENKO KK (JP) 2007-04-18 EP disclosed
EP-1182184-B1 PROCESS FOR PRODUCING TETRAFLUORO BENZENECARBALDEHYDES AND TETRAFLUORO BENZENEMETHANOLS SHOWA DENKO KK (JP) 2007-04-18 EP disclosed
CN-1237037-C Process for producing tetrafluoro benzenemethanols SHOWA DENKO KK (JP) 2006-01-18 CN disclosed
US-6624336-B1 Acetalization of tetrafluorobenzonitriles using alcohols, in the presence of mineral acids and metal catalysts to form chemical intermediates for nontoxic insecticides SHOWA DENKO K.K. (JP) 2003-09-23 US disclosed
CN-1349484-A Process for producing tetrafluorobenzyl alcohol SHOWA DENKO KK (JP) 2002-05-15 CN disclosed
EP-1182184-A1 PROCESS FOR PRODUCING TETRAFLUORO BENZENEMETHANOLS Showa Denko K K (JP) 2002-02-27 EP disclosed