Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 7/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.52 |
| ▸ | PTGIR | P43119 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15792614 | 0.83 | PTGDR (0.54) | PTGDRTBXA2RPTGIRSMN1; SMN2HTT | |
| SCHEMBL6483025 | 0.75 | ALDH1A1 (0.41) | SMN1; SMN2HTTALDH1A1HPGDMEN1 | |
| SCHEMBL13538399 | 0.75 | PSEN1 (0.61) | TBXA2RALDH1A1KMT2AMMP13MMP8 | |
| SCHEMBL23613809 | 0.74 | MMP12 (0.60) | SMN1; SMN2HTTALDH1A1HPGDMEN1 | |
| SCHEMBL15896281 | 0.74 | MMP12 (0.60) | SMN1; SMN2HTTALDH1A1HPGDMEN1 | |
| SCHEMBL28714130 | 0.73 | PSEN1 (0.51) | PTGDRTBXA2RPTGIRHTTMEN1 | |
| SCHEMBL6858450 | 0.72 | UCHL1 (0.50) | PTGDRSMN1; SMN2HTTALDH1A1HPGD | |
| SCHEMBL30807175 | 0.72 | PARG (0.52) | SMN1; SMN2HTTALDH1A1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL6580187 | 0.71 | SMN1; SMN2 (0.47) | PTGDRTBXA2RPTGIRSMN1; SMN2HTT | |
| SCHEMBL9094331 | 0.70 | CYP1A2 (0.49) | ALDH1A1MEN1KMT2ATP53HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028969-A1 | BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS AND USES THEREOF | NOVARTIS AG (CH) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028969-A1 | BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS AND USES THEREOF | ACACA, ACACB, COASY | PTGDR 4481/4885TBXA2R 2202/4885PTGIR 2559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.