Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | PRKDC | P78527 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5167771 | 0.83 | SIRT6 (0.52) | CTSBSMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL6601670 | 0.83 | MAPT (0.51) | CTSBLMNAMAPTALDH1A1CYP1A2 | |
| SCHEMBL4871412 | 0.77 | CTSB (1.00) | CTSBKMT2ASMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL5168060 | 0.74 | KDM4E (0.48) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL17065812 | 0.74 | PRKDC (0.46) | KMT2AL3MBTL1LMNAMAPTALDH1A1 | |
| SCHEMBL3984049 | 0.74 | CYP1A2 (0.54) | CTSBKMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL31226524 | 0.74 | CYP1A2 (0.54) | CTSBKMT2ASMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL8095201 | 0.74 | MAPT (0.50) | CTSBKMT2ASMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL3723155 | 0.74 | CYP1A2 (0.54) | CTSBSMN1; SMN2L3MBTL1LMNAMAPT | |
| SCHEMBL30457932 | 0.74 | ALDH1A1 (0.63) | CTSBKMT2ASMN1; SMN2MEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007054836-A2 | 1, 2-SUBSTITUTED NAPHTHALENE DERIVATIVES WITH ANTIGLUTAMATERGIC PROPERTIES AND USES THEREOF | FAUST PHARMACEUTICALS (FR) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007054836-A2 | 1, 2-SUBSTITUTED NAPHTHALENE DERIVATIVES WITH ANTIGLUTAMATERGIC PROPERTIES AND USES THEREOF | FAUST PHARMACEUTICALS (FR) | 2007-05-18 | — | — | WO | disclosed |
| EP-1777219-A1 | 1,2-Substituted naphthalene derivatives with antiglutamatergic properties and uses thereof | Faust Pharmaceuticals (FR) | 2007-04-25 | — | — | EP | disclosed |