SCHEMBL516891

SCHEMBL516891

O=C(NC1CCCCC1)c1ccccc1-c1ccccc1C(=O)NC1CCCCC1

nearest known ligand 0.82

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.82
SMN1; SMN2 Q16637 3/20 0.82
LMNA P02545 2/20 0.82
MEN1 O00255 1/20 0.82
KMT2A Q03164 1/20 0.82
NPSR1 Q6W5P4 1/20 0.82
GAA P10253 4/20 0.79
NPC1 O15118 3/20 0.73
RAB9A P51151 3/20 0.73
KDM4E B2RXH2 3/20 0.73
HPGD P15428 2/20 0.73
HTT P42858 2/20 0.73
POLB P06746 2/20 0.63
MAPT P10636 2/20 0.62
PKM P14618 1/20 0.62
APOBEC3G Q9HC16 1/20 0.59
SGMS2 Q8NHU3 1/20 0.57
L3MBTL1 Q9Y468 2/20 0.56
EPHX2 P34913 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30666379 0.89 ALDH1A1 (0.77) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL14614940 0.84 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL984084 0.84 ALDH1A1 (0.71) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL4768123 0.83 RAB9A (0.68) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL12181533 0.83 NPC1 (0.69) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL10793476 0.83 GAA (0.77) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL3455151 0.83 NPC1 (0.69) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL8198182 0.83 NPC1 (1.00) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL3081280 0.83 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL2154833 0.83 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2392458-B1 POLYPROPYLENE RESIN MOLDED ARTICLE NEW JAPAN CHEM CO LTD (JP) 2018-03-14 EP disclosed
US-9287543-B2 Porous film, separator for electric storage device, and electric storage device TORAY INDUSTRIES, INC. (JP) 2016-03-15 US disclosed
US-9023921-B2 Method for inhibiting crystal growth rate of amide compound and method for producing molded article of polyolefin-based resin NEW JAPAN CHEMICAL CO., LTD. (JP) 2015-05-05 US disclosed
EP-2671909-A1 POROUS FILM, SEPARATOR FOR ELECTRICITY-STORING DEVICE, AND ELECTRICITY-STORING DEVICE Toray Industries, Inc. (JP) 2013-12-11 EP disclosed
US-20130316246-A1 POROUS FILM, SEPARATOR FOR ELECTRIC STORAGE DEVICE, AND ELECTRIC STORAGE DEVICE TORAY INDUSTRIES, INC. (JP) 2013-11-28 US disclosed
EP-2431415-A1 METHOD FOR CONTROLLING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN New Japan Chemical Co., Ltd. (JP) 2012-03-21 EP disclosed
US-20120035304-A1 METHOD FOR INHIBITING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN NEW JAPAN CHEMICAL CO., LTD. (JP) 2012-02-09 US disclosed
US-20120028006-A1 POLYPROPYLENE RESIN MOLDED ARTICLE NEW JAPAN CHEMICAL CO., LTD. (JP) 2012-02-02 US disclosed
EP-2392458-A2 POLYPROPYLENE RESIN MOLDED ARTICLE New Japan Chemical Co., Ltd. (JP) 2011-12-07 EP disclosed
EP-0962489-B1 Crystalline polypropylene resin composition and amide compounds NEW JAPAN CHEM CO LTD (JP) 2004-09-15 EP disclosed
WO-2004031090-A2 SCRATCH-RESISTANT COATING COMPOSITION AND METHOD FOR THE PRODUCTION THEREOF BAYER MATERIALSCIENCE AG (DE) 2004-04-15 WO disclosed
US-6235823-B1 CRYSTALLINE POLYPROPLYLENE RESIN AND A BETA-NUCLEATING AGENT, THE BETA-NUCLEATING AGENT BEING A DIAMIDE COMPOUND. NEW JAPAN CHEMICAL CO., LTD. (JP) 2001-05-22 US disclosed
EP-0557721-B1 Polypropylene moulded articles with increased -crystal content and bisamides as -nucleating agents. NEW JAPAN CHEM CO LTD (JP) 2000-10-04 EP disclosed
EP-0962489-A2 Crystalline polypropylene resin composition and amide compounds NEW JAPAN CHEMICAL CO.,LTD. (JP) 1999-12-08 EP disclosed
EP-0557721-A2 Crystalline polypropylene resin composition and amide compounds NEW JAPAN CHEMICAL CO.,LTD. (JP) 1993-09-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035304-A1 METHOD FOR INHIBITING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN MNAT1, RFT1, RTF1 ALDH1A1 2124/4885SMN1; SMN2 3244/4885LMNA 3737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.