Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 2/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5166698 | 0.86 | SIGMAR1 (0.51) | ESRRGTMEM97SIGMAR1ACHENR1H4 | |
| SCHEMBL6249909 | 0.85 | MAPT (0.52) | ESRRGTMEM97SIGMAR1NR1H4EPHX2 | |
| SCHEMBL5166498 | 0.85 | MAOA (0.50) | ESRRGTMEM97SIGMAR1ACHENR1H4 | |
| SCHEMBL5166575 | 0.84 | SIGMAR1 (0.45) | ESRRGTMEM97SIGMAR1ACHENR1H4 | |
| SCHEMBL5167540 | 0.84 | ACHE (0.45) | TMEM97SIGMAR1ACHEHDAC6HDAC11 | |
| SCHEMBL5169424 | 0.83 | LMNA (0.46) | ESRRGTMEM97SIGMAR1ACHENR1H4 | |
| SCHEMBL5182136 | 0.83 | MEN1 (0.55) | TMEM97SIGMAR1NR1H4EPHX2TP53 | |
| SCHEMBL5167511 | 0.82 | PPARG (0.49) | ESRRGTMEM97SIGMAR1ACHENR1H4 | |
| SCHEMBL6249114 | 0.81 | NR1H4 (0.54) | ESRRGTMEM97SIGMAR1NR1H4EPHX2 | |
| SCHEMBL6249120 | 0.81 | MAPT (0.60) | ESRRGTMEM97SIGMAR1ACHENR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329399-B1 | Antifungal amine derivatives and processing for producing the same | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2001-12-11 | — | — | US | claimed |
| EP-1020426-A1 | AMINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-07-19 | — | — | EP | claimed |
| EP-1561744-B1 | AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS ANTIMYCOTIC AGENT | POLA CHEM IND INC (JP) | 2007-04-18 | — | — | EP | disclosed |
| EP-1561744-A2 | AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS ANTIMYCOTIC AGENT | POLA CHEMICAL INDUSTRIES INC. (JP) | 2005-08-10 | — | — | EP | disclosed |
| US-6329399-B1 | Antifungal amine derivatives and processing for producing the same | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1020426-A1 | AMINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-07-19 | — | — | EP | disclosed |