Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2085835 | 0.93 | LMNA (0.41) | MTNR1AMTNR1BADRB1ADRB3SMN1; SMN2 | |
| SCHEMBL2081800 | 0.78 | FFAR1 (0.50) | LMNAKMT2A | |
| SCHEMBL4211215 | 0.75 | CAPN1 (0.46) | SMN1; SMN2LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL4218382 | 0.74 | KMT2A (0.44) | MTNR1AMTNR1BSMN1; SMN2LMNAGLA | |
| SCHEMBL4211218 | 0.74 | KMT2A (0.44) | MTNR1AMTNR1BSMN1; SMN2LMNAGLA | |
| SCHEMBL4211214 | 0.74 | KMT2A (0.44) | MTNR1AMTNR1BSMN1; SMN2LMNAGLA | |
| SCHEMBL2084192 | 0.73 | MTNR1A (0.44) | MTNR1AMTNR1B | |
| SCHEMBL5561305 | 0.73 | NPY5R (0.43) | LMNAALDH1A1 | |
| SCHEMBL2084264 | 0.72 | DRD2 (0.41) | — | |
| SCHEMBL2084806 | 0.72 | LTB4R (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781297-A1 | NOVEL BIAROMATIC COMPOUNDS THAT ACTIVATE PPAR TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006018326-A1 | NOVEL BIAROMATIC COMPOUNDS THAT ACTIVATE PPAR TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2006-02-23 | — | — | WO | disclosed |