Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 7/20 | 0.77 |
| ▸ | HTR1A | P08908 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.61 |
| ▸ | JAK2 | O60674 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635445 | 0.88 | MPO (0.73) | MPOHTR1AGPR84DRD2DRD4 | |
| SCHEMBL13499605 | 0.87 | MPO (1.00) | MPOHTR1AGPR84DRD2DRD4 | |
| SCHEMBL733997 | 0.85 | MPO (1.00) | MPOHTR1AHTR2A | |
| SCHEMBL14375346 | 0.85 | MPO (0.72) | MPOHTR1AMAPK1GPR84DRD2 | |
| SCHEMBL733711 | 0.84 | MPO (0.97) | MPOHTR1AHTR2A | |
| SCHEMBL13375737 | 0.83 | MPO (0.69) | MPOHTR1AMAPK1GPR84DRD2 | |
| SCHEMBL26508398 | 0.82 | MPO (0.94) | MPOHTR1AHTR2A | |
| SCHEMBL5197968 | 0.82 | LMNA (0.61) | MPOKDM4ELMNAHTTMAPK1 | |
| SCHEMBL13374358 | 0.82 | MPO (0.67) | MPOHTR1AMAPK1GPR84DRD2 | |
| SCHEMBL8789588 | 0.81 | LMNA (0.64) | MPOHTR1AKDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |