SCHEMBL517318

SCHEMBL517318

CC1CCCCC1NC(=O)c1ccc2cc(C(=O)NC3CCCCC3C)ccc2c1

nearest known ligand 0.72

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 16/20 0.72
TAS1R1 Q7RTX1 15/20 0.72
TAS1R2 Q8TE23 14/20 0.72
MLYCD O95822 1/20 0.63
ALDH1A1 P00352 2/20 0.56
USP2 O75604 1/20 0.56
LMNA P02545 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22462400 0.93 TAS1R3 (0.64) TAS1R3TAS1R1TAS1R2MLYCDALDH1A1
SCHEMBL517994 0.89 MLYCD (0.77) TAS1R3TAS1R1TAS1R2MLYCDALDH1A1
SCHEMBL518128 0.88 RAB9A (0.68) TAS1R3TAS1R1TAS1R2ALDH1A1
SCHEMBL2453198 0.85 TAS1R3 (0.81) TAS1R3TAS1R1TAS1R2MLYCD
SCHEMBL5272688 0.85 TAS1R3 (0.68) TAS1R3TAS1R1TAS1R2MLYCD
SCHEMBL517895 0.84 MLYCD (0.71) TAS1R3TAS1R1TAS1R2MLYCDALDH1A1
SCHEMBL700604 0.84 TAS1R3 (1.00) TAS1R3TAS1R1TAS1R2MLYCDALDH1A1
SCHEMBL701892 0.84 TAS1R3 (1.00) TAS1R3TAS1R1TAS1R2MLYCDALDH1A1
SCHEMBL12858941 0.83 RAB9A (0.62) TAS1R3TAS1R1TAS1R2ALDH1A1
SCHEMBL4175029 0.83 TAS1R3 (0.72) TAS1R3TAS1R1TAS1R2MLYCDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200384678-A1 DECORATIVE FILM AND METHOD FOR MANUFACTURING DECORATIVE MOLDED ARTICLE USING SAME JAPAN POLYPROPYLENE CORPORATION (JP) 2020-12-10 US disclosed
EP-3715092-A1 DECORATIVE FILM AND METHOD FOR MANUFACTURING DECORATIVE MOLDED ARTICLE USING SAME Japan Polypropylene Corporation (JP) 2020-09-30 EP disclosed
EP-2392458-B1 POLYPROPYLENE RESIN MOLDED ARTICLE NEW JAPAN CHEM CO LTD (JP) 2018-03-14 EP disclosed
US-9023921-B2 Method for inhibiting crystal growth rate of amide compound and method for producing molded article of polyolefin-based resin NEW JAPAN CHEMICAL CO., LTD. (JP) 2015-05-05 US disclosed
EP-2431415-A1 METHOD FOR CONTROLLING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN New Japan Chemical Co., Ltd. (JP) 2012-03-21 EP disclosed
US-20120035304-A1 METHOD FOR INHIBITING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN NEW JAPAN CHEMICAL CO., LTD. (JP) 2012-02-09 US disclosed
US-20120028006-A1 POLYPROPYLENE RESIN MOLDED ARTICLE NEW JAPAN CHEMICAL CO., LTD. (JP) 2012-02-02 US disclosed
EP-2392458-A2 POLYPROPYLENE RESIN MOLDED ARTICLE New Japan Chemical Co., Ltd. (JP) 2011-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035304-A1 METHOD FOR INHIBITING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN MNAT1, RFT1, RTF1 TAS1R3 1107/4885TAS1R1 597/4885TAS1R2 987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.