SCHEMBL517335

SCHEMBL517335

C=CC(=O)OCC(F)(F)C(F)F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
TP53 P04637 3/20 0.52
HIF1A Q16665 3/20 0.52
CYP3A4 P08684 2/20 0.52
MAPK1 P28482 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
TSHR P16473 9/20 0.44
HSD17B10 Q99714 1/20 0.42
THRB P10828 1/20 0.40
HPGD P15428 1/20 0.38
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
LMNA P02545 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
KDM4E B2RXH2 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9242879 0.87 ALDH1A1 (0.41) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL15297213 0.86 ALDH1A1 (0.51) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL15297262 0.86 ALDH1A1 (0.51) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL12912827 0.85 ALDH1A1 (0.46) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL372552 0.85 ALDH1A1 (0.48) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL26362955 0.85 TSHR (0.50) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL11035102 0.84 ALDH1A1 (0.43) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL5945804 0.83 TSHR (0.39) ALDH1A1MAPK1TSHRPOLBGAA
SCHEMBL5945800 0.83 TSHR (0.39) ALDH1A1MAPK1TSHRPOLBGAA
SCHEMBL9719157 0.83 TSHR (0.39) ALDH1A1MAPK1TSHRPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022277-A1 CURABLE COMPOSITIONS ARKEMA FRANCE (FR) 2026-01-22 US claimed
US-20250385306-A1 FLUORINATED POLYMER ELECTROLYTE FOR ELECTROCHEMICAL CELLS GM GLOBAL TECH OPERATIONS LLC (US) 2025-12-18 US claimed
WO-2025151080-A1 POLYMER ELECTROLYTES NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-07-17 WO claimed
US-12336322-B2 Transparent luminescent solar concentrator BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2025-06-17 US claimed
EP-3571548-B1 COLOR ORGANIC PIGMENTS AND ELECTROPHORETIC DISPLAY MEDIA CONTAINING THE SAME E INK CORP (US) 2025-06-11 EP claimed
EP-4558534-A1 CURABLE COMPOSITIONS ARKEMA FRANCE (FR) 2025-05-28 EP claimed
WO-2024259629-A1 MODIFIED CURRENT COLLECTOR FOR SECONDARY BATTERY GUANGDONG HAOZHI TECHNOLOGY CO. LIMITED (CN) 2024-12-26 WO claimed
WO-2024018040-A1 CURABLE COMPOSITIONS ARKEMA FRANCE (FR) 2024-01-25 WO claimed
EP-4310117-A1 CURABLE COMPOSITIONS ARKEMA FRANCE (FR) 2024-01-24 EP claimed
US-11738366-B2 Method of coating an object THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-08-29 US claimed
US-5288825-A Fluoroalkyl acrylate or methacrylate copolymer; stain resistance, lubricants MITSUBISHI RAYON COMPANY LTD. (JP) 1994-02-22 US claimed
EP-0294976-B1 Non-hydrous soft contact lens and process for producing the same JAPAN SYNTHETIC RUBBER CO LTD (JP) 1994-01-05 EP claimed
EP-0484163-A2 Liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 1992-05-06 EP claimed
EP-0449274-A1 Fluoroacrylic polymer having lubricating effect and thermoplastic resin composition comprising same MITSUBISHI RAYON COMPANY, LTD. (JP) 1991-10-02 EP claimed
US-4882403-A Non-hydrous soft contact lens and process for producing the same JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1989-11-21 US claimed
EP-0294976-A2 Non-hydrous soft contact lens and process for producing the same CIBA-GEIGY AG (CH) 1988-12-14 EP claimed
EP-0098578-B1 PLASTIC OPTICAL FIBERS MITSUBISHI RAYON CO., LTD. (JP) 1987-04-01 EP claimed
US-4593974-A Plastic optical fiber MITSUBISHI RAYON CO., LTD. (JP) 1986-06-10 US claimed
US-4544235-A RADIATION TRANSPARETN HOMO AND COPOLYMERS COMNPRISING A CORE AND C MITSUBISHI RAYON CO., LTD. (JP) 1985-10-01 US claimed
EP-0098578-A1 Plastic optical fibers MITSUBISHI RAYON CO., LTD. (JP) 1984-01-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022277-A1 CURABLE COMPOSITIONS MTDH, MYO1G, TPM3 ALDH1A1 1130/4885TP53 1705/4885HIF1A 3182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.