Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5945804 | 1.00 | TSHR (0.39) | TSHRPOLBGAAALDH1A1NPSR1 | |
| SCHEMBL5945800 | 1.00 | TSHR (0.39) | TSHRPOLBGAAALDH1A1NPSR1 | |
| SCHEMBL13386033 | 0.88 | TSHR (0.33) | TSHRPOLBGAAALDH1A1NPSR1 | |
| SCHEMBL517335 | 0.83 | ALDH1A1 (0.52) | TSHRPOLBGAAALDH1A1NPSR1 | |
| SCHEMBL308634 | 0.79 | TSHR (0.41) | TSHRPOLBGAAALDH1A1NPSR1 | |
| SCHEMBL13662454 | 0.77 | TSHR (0.34) | TSHRPOLBGAAALDH1A1NPSR1 | |
| SCHEMBL27220786 | 0.77 | TSHR (0.41) | TSHRPOLBGAAALDH1A1NPSR1 | |
| SCHEMBL25858052 | 0.77 | HTT (0.43) | TSHRPOLBGAAALDH1A1NPSR1 | |
| SCHEMBL308635 | 0.77 | LMNA (0.43) | TSHRPOLBGAAALDH1A1NPSR1 | |
| SCHEMBL581271 | 0.77 | POLB (0.64) | TSHRPOLBGAAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933406-A | OXYGEN-PERMEABLE, RIGID | NIPPON OIL AND FATS CO., LTD. (JP) | 1990-06-12 | — | — | US | claimed |
| US-5142009-A | Crosslinked blend of fumaric acid diesters | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-4933406-A | OXYGEN-PERMEABLE, RIGID | NIPPON OIL AND FATS CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| US-4868260-A | OXYGEN PERMEABILITY | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1989-09-19 | — | — | US | disclosed |