Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5174650 | 1.00 | CHRNB2 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4MAPT | |
| SCHEMBL24859121 | 0.82 | CASP1 (0.40) | CASP1CYP3A4LMNA | |
| SCHEMBL28176134 | 0.82 | CASP1 (0.40) | CASP1CYP3A4LMNA | |
| SCHEMBL14175059 | 0.82 | CASP1 (0.36) | CHRNB2CHRNA4MAPTCASP1CYP3A4 | |
| SCHEMBL5175654 | 0.80 | TSHR (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4MAPT | |
| SCHEMBL28550739 | 0.80 | ESR1 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4MAPT | |
| SCHEMBL5176139 | 0.80 | TSHR (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4MAPT | |
| SCHEMBL4859222 | 0.80 | TSHR (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4MAPT | |
| SCHEMBL11462249 | 0.79 | ITGB2 (0.35) | MAPTESR1CYP3A4LMNA | |
| SCHEMBL14175139 | 0.78 | ALDH1A1 (0.35) | CASP1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3302471-A1 | TETRASUBSTITUTED ALKENE COMPOUNDS AND THEIR USE | Eisai R&D Management Co., Ltd. (JP) | 2018-04-11 | — | — | EP | disclosed |
| CN-107847498-A | tetra-substituted olefin compound and use thereof | 卫材R&D管理有限公司 | 2018-03-27 | — | — | CN | disclosed |
| WO-2016196346-A1 | TETRASUBSTITUTED ALKENE COMPOUNDS AND THEIR USE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2016-12-08 | — | — | WO | disclosed |
| EP-1281516-B1 | Planographic printing plate precursor | FUJIFILM CORP (JP) | 2007-12-19 | — | — | EP | disclosed |
| EP-1602481-B1 | Lithographic printing plate precursor | FUJIFILM CORP (JP) | 2007-05-30 | — | — | EP | disclosed |
| EP-1203659-B1 | Lithographic printing plate precursor | FUJI PHOTO FILM CO LTD (JP) | 2006-05-17 | — | — | EP | disclosed |
| EP-1602481-A1 | Lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-6951171-B2 | Using graft polymer on etched or anodized aluminum substrate | FUJI PHOTO FILM CO., LTD. (JP) | 2005-10-04 | — | — | US | disclosed |
| EP-1371500-B1 | Lithographic printing plate precursor | FUJI PHOTO FILM CO LTD (JP) | 2005-09-28 | — | — | EP | disclosed |
| US-6939658-B2 | Lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2005-09-06 | — | — | US | disclosed |
| US-20030190553-A1 | Support with hydrophilic surface; multilayer; latex layer and ink receiver | FUJIFILM CORPORATION (JP) | 2003-10-09 | — | — | US | disclosed |
| US-20030129520-A1 | Using graft polymer on etched or anodized aluminum substrate | FUJIFILM CORPORATION (JP) | 2003-07-10 | — | — | US | disclosed |
| EP-1281516-A2 | Planographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2003-02-05 | — | — | EP | disclosed |
| US-6509132-B1 | Comprises an ink-receptive image area for receiving ink during the printing process and a hydrophilic non-image area for receiving fountain solution | FUJI PHOTO FILM CO., LTD. (JP) | 2003-01-21 | — | — | US | disclosed |
| US-6455224-B1 | SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE | FUJI PHOTO FILM CO., LTD. (JP) | 2002-09-24 | — | — | US | disclosed |
| US-20020068241-A1 | Lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2002-06-06 | — | — | US | disclosed |
| EP-1203659-A2 | Lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2002-05-08 | — | — | EP | disclosed |
| EP-1136281-A1 | Lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2001-09-26 | — | — | EP | disclosed |
| EP-1048457-A2 | Lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |
| EP-1031414-A1 | Lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2000-08-30 | — | — | EP | disclosed |