Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9323714 | 0.85 | MYC (0.37) | ELANEALDH1A1HSD17B10TDP1HTR6 | |
| SCHEMBL5175522 | 0.83 | CA1 (0.46) | CYP2C9CA1CA2CA5ACA9 | |
| SCHEMBL7257591 | 0.83 | PTGS2 (0.50) | TRPV4ALDH1A1HSD17B10TDP1CYP1A2 | |
| SCHEMBL11199429 | 0.83 | BCAT2 (0.40) | ELANEHTR6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11070094 | 0.80 | TRPV4 (0.34) | TRPV4ELANEALDH1A1HSD17B10TDP1 | |
| SCHEMBL20582067 | 0.80 | ELANE (0.57) | ELANEALDH1A1CA2MAPT | |
| SCHEMBL11070115 | 0.80 | TRPV4 (0.34) | TRPV4ELANEALDH1A1HSD17B10TDP1 | |
| SCHEMBL11242849 | 0.80 | KMT2A (0.56) | HSD17B10TDP1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL30524282 | 0.79 | SERPINE1 (0.43) | ELANEALDH1A1HSD17B10TDP1CYP1A2 | |
| SCHEMBL5696260 | 0.79 | SERPINE1 (0.43) | ELANEALDH1A1HSD17B10TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747231-A1 | AMINOSULPHONYL- OR AMINOSULPHONYLAMINO-SUBSTITUTED PHENYL ESTERS AS ESTRIOL AND ESTETROL PRODRUGS | Schering Aktiengesellschaft (DE) | 2007-01-31 | — | — | EP | disclosed |
| EP-1747229-A1 | STEROID PRODRUGS WITH ANDROGENIC EFFECT | Schering Aktiengesellschaft (DE) | 2007-01-31 | — | — | EP | disclosed |
| EP-1747230-A1 | AMINOSULPHONYL-OR AMINOSULPHONYLAMINO-SUBSTITUTED PHENYL ESTERS AS ESTRADIOL PRODRUGS | Schering Aktiengesellschaft (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005113574-A1 | AMINOSULPHONYL- OR AMINOSULPHONYLAMINO-SUBSTITUTED PHENYL ESTERS AS ESTRADIOL PRODRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-12-01 | — | — | WO | disclosed |
| WO-2005113576-A1 | AMINOSULPHONYL- OR AMINOSULPHONYLAMINO-SUBSTITUTED PHENYL ESTERS AS ESTRIOL AND ESTETROL PRODRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-12-01 | — | — | WO | disclosed |
| WO-2005113575-A1 | STEROID PRODRUGS WITH ANDROGENIC EFFECT | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-12-01 | — | — | WO | disclosed |