Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | LTA4H | P09960 | 3/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24041796 | 0.91 | FFAR1 (0.68) | FFAR1NPC1RAB9ATDP1LTA4H | |
| SCHEMBL19102211 | 0.90 | ALDH1A1 (0.69) | FFAR1NPC1RAB9ATDP1LTA4H | |
| SCHEMBL24041843 | 0.90 | ALDH1A1 (0.63) | FFAR1NPC1RAB9ATDP1LTA4H | |
| SCHEMBL4165319 | 0.89 | FFAR1 (0.69) | FFAR1TDP1LTA4HEPHX2ALDH1A1 | |
| SCHEMBL5391064 | 0.89 | FFAR1 (0.67) | FFAR1NPC1RAB9ALTA4HEPHX2 | |
| SCHEMBL8767634 | 0.89 | KCNA3 (0.61) | FFAR1TDP1LTA4HEPHX2ALDH1A1 | |
| SCHEMBL9456979 | 0.88 | NPC1 (0.80) | FFAR1NPC1RAB9ALTA4HCA12 | |
| SCHEMBL8500544 | 0.87 | FFAR1 (0.67) | FFAR1TDP1LTA4HEPHX2ALDH1A1 | |
| SCHEMBL8408714 | 0.86 | ALDH1A1 (0.69) | FFAR1NPC1RAB9ATDP1LTA4H | |
| SCHEMBL6658231 | 0.86 | HRH3 (0.59) | FFAR1TDP1LTA4HEPHX2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102898289-B | Method for synthesizing 2-(4-benzylmethoxyphenyl)ethanol medical intermediate | Jiangsu defeng pharmaceutical co ltd | 2014-09-03 | — | — | CN | disclosed |
| CN-102898289-B | Method for synthesizing 2-(4-benzylmethoxyphenyl)ethanol medical intermediate | Jiangsu defeng pharmaceutical co ltd | 2014-09-03 | — | — | CN | disclosed |
| CN-102898289-A | Method for synthesizing 2-(4-benzylmethoxyphenyl)ethanol medical intermediate | Jiangsu defeng pharmaceutical co ltd | 2013-01-30 | — | — | CN | disclosed |
| CN-102898289-A | Method for synthesizing 2-(4-benzylmethoxyphenyl)ethanol medical intermediate | Jiangsu defeng pharmaceutical co ltd | 2013-01-30 | — | — | CN | disclosed |
| CN-100384836-C | Novel cyclic amide derivative | MITSUBISHI PHARMACEUTICALS INC (JP) | 2008-04-30 | — | — | CN | disclosed |
| EP-1868605-A2 | PHENYL AND PYRIDYL LTA4H MODULATORS | Janssen Pharmaceutica, N.V. (BE) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006105304-A2 | PHENYL AND PYRIDYL LTA4H MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-10-05 | — | — | WO | disclosed |
| US-20060223792-A1 | Phenyl and pyridyl LTA4H modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-10-05 | — | — | US | disclosed |
| CN-1426405-A | Novel cyclic amide derivative | MITSUBISHI PHARMACEUTICALS INC (JP) | 2003-06-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223792-A1 | Phenyl and pyridyl LTA4H modulators | LTA4H, LTB4R, LTC4S | FFAR1 532/4885NPC1 1667/4885RAB9A 4254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.