Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | PNP | P00491 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 2/20 | 0.43 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565290 | 0.86 | KDM4E (0.43) | KDM4ETSHRNPSR1CYP19A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30496762 | 0.77 | KMT2A (0.47) | LMNAALDH1A1POLBHTT | |
| SCHEMBL5176030 | 0.76 | CYP3A4 (0.53) | KDM4ETSHRNPSR1CYP19A1SMN1; SMN2 | |
| SCHEMBL15554598 | 0.73 | KDM4E (0.50) | KDM4ETSHRNPSR1CYP19A1SMN1; SMN2 | |
| SCHEMBL9504656 | 0.73 | KDM4E (0.60) | KDM4ETSHRNPSR1CYP19A1SMN1; SMN2 | |
| SCHEMBL939417 | 0.72 | TNF (0.79) | KDM4ETSHRLMNAALDH1A1POLB | |
| SCHEMBL2163180 | 0.72 | LMNA (0.59) | KDM4ETSHRLMNAHPGDALDH1A1 | |
| SCHEMBL8985073 | 0.70 | GSK3B (0.67) | KDM4ECYP19A1SMN1; SMN2LMNAGSK3A | |
| SCHEMBL25171603 | 0.69 | TNF (0.51) | KDM4ECYP19A1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL14160787 | 0.68 | KDM4E (0.50) | KDM4ETSHRNPSR1CYP19A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737417-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005074875-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-08-18 | — | — | WO | disclosed |