SCHEMBL9504656

SCHEMBL9504656

Cc1nnc(C)n1Cc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.60
NPSR1 Q6W5P4 2/20 0.60
TSHR P16473 2/20 0.60
TNF P01375 1/20 0.56
POLB P06746 1/20 0.55
BRD4 O60885 6/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2C9 P11712 1/20 0.53
ALDH1A1 P00352 3/20 0.50
LMNA P02545 3/20 0.50
AVPR1A P37288 1/20 0.50
MAPK1 P28482 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
CYP19A1 P11511 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 P62805 1/20 0.48
GSK3A P49840 1/20 0.47
GSK3B P49841 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10480363 0.86 KDM4E (0.51) KDM4ENPSR1TSHRTNFPOLB
SCHEMBL22680657 0.83 BRD4 (0.49) KDM4ENPSR1TSHRTNFPOLB
SCHEMBL9950749 0.82 KDM4E (0.47) KDM4ENPSR1TSHRTNFPOLB
SCHEMBL6403164 0.80 LMNA (0.65) KDM4ENPSR1TSHRPOLBALDH1A1
SCHEMBL12596382 0.80 POLB (0.61) KDM4ETNFPOLBALDH1A1LMNA
SCHEMBL14557080 0.78 L3MBTL1 (0.57) KDM4ENPSR1TSHRPOLBBRD4
SCHEMBL6521231 0.76 KDM4E (0.59) KDM4ENPSR1TSHRTNFPOLB
SCHEMBL4735710 0.76 ALDH1A1 (0.71) KDM4ENPSR1CYP3A4ALDH1A1LMNA
SCHEMBL8814077 0.76 ALDH1A1 (0.49) KDM4ENPSR1TSHRTNFCYP1A2
SCHEMBL11151151 0.75 ALDH1A1 (0.59) KDM4ENPSR1TSHRTNFPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0322003-B1 AZOMETHINE DYE DERIVED FROM A COMPOUND HAVING A PYRAZOLO TRIAZOLE MOIETY FUJI PHOTO FILM CO., LTD. (JP) 1993-06-23 EP disclosed
EP-0119860-B1 PYRAZOLO MAGENTA COUPLERS USED IN SILVER HALIDE PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1989-10-25 EP disclosed
EP-0322003-A2 Azomethine dye derived from a compound having a pyrazolo triazole moiety FUJI PHOTO FILM CO., LTD. (JP) 1989-06-28 EP disclosed
US-4621046-A MAGENTA COLOR IMAGE FORMING COUPLERS FUJI PHOTO FILM CO., LTD. (JP) 1986-11-04 US disclosed
US-4540654-A Method of forming color image comprising heterocyclic magenta dye-forming coupler FUJI PHOTO FILM CO., LTD. (JP) 1985-09-10 US disclosed
EP-0119860-A2 Pyrazolo magenta couplers used in silver halide photography FUJI PHOTO FILM CO., LTD. (JP) 1984-09-26 EP disclosed