Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL595607 | 0.78 | ALDH1A1 (0.34) | PIM1GRM2GRM3MAPTNPSR1 | |
| SCHEMBL5175388 | 0.76 | PIM1 (0.40) | PIM1GRM2GRM3SLC9A1ALDH1A1 | |
| SCHEMBL8772911 | 0.73 | MAPT (0.40) | PIM1GRM2GRM3NPC1MAPT | |
| SCHEMBL28728918 | 0.69 | ACHE (0.36) | PIM1GRM2GRM3ACHE | |
| SCHEMBL900729 | 0.68 | SMN1; SMN2 (0.49) | PIM1MAPTHTTACHEALDH1A1 | |
| SCHEMBL16555709 | 0.68 | LMNA (0.39) | PIM1NPC1MAPTHTTRAB9A | |
| SCHEMBL13751211 | 0.68 | PIM1 (0.34) | PIM1GRM2GRM3ACHESLC9A1 | |
| SCHEMBL9475992 | 0.67 | MAPT (0.37) | PIM1GRM2GRM3MAPTACHE | |
| SCHEMBL15231537 | 0.66 | CA12 (0.38) | — | |
| SCHEMBL25683797 | 0.65 | PIM1 (0.41) | PIM1ACHEPTPN7DUSP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867636-A1 | PYRIDYLMETHYLSULFONE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2007-12-19 | — | — | EP | disclosed |