SCHEMBL5176152

SCHEMBL5176152

C/C=C/C(=O)OCc1ccccc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.48
RAB9A P51151 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
CASP3 P42574 3/20 0.47
SENP8 Q96LD8 3/20 0.47
SENP7 Q9BQF6 3/20 0.47
SENP6 Q9GZR1 3/20 0.47
MMP1 P03956 1/20 0.47
MMP2 P08253 1/20 0.47
MMP9 P14780 1/20 0.47
MMP12 P39900 1/20 0.47
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
NPC1 O15118 1/20 0.46
ALDH1A1 P00352 1/20 0.45
HTT P42858 1/20 0.45
IDO1 P14902 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11743721 1.00 MAPT (0.48) MAPTRAB9AL3MBTL1CASP3SENP8
SCHEMBL9064620 0.90 L3MBTL1 (0.53) MAPTRAB9AL3MBTL1CASP3SENP8
SCHEMBL7089089 0.90 L3MBTL1 (0.53) MAPTRAB9AL3MBTL1CASP3SENP8
SCHEMBL7086104 0.90 L3MBTL1 (0.53) MAPTRAB9AL3MBTL1CASP3SENP8
SCHEMBL5808206 0.87 RAB9A (0.50) MAPTRAB9AL3MBTL1CASP3SENP8
SCHEMBL27966346 0.84 HCAR2 (0.63) MAPTRAB9AL3MBTL1CASP3SENP8
SCHEMBL14937097 0.82 MAOB (0.45) MAPTRAB9AL3MBTL1MAOBNPC1
SCHEMBL14937098 0.82 MAOB (0.45) MAPTRAB9AL3MBTL1MAOBNPC1
SCHEMBL5176891 0.82 IDO1 (0.46) IDO1LMNAHCAR2GSTP1
SCHEMBL961210 0.80 L3MBTL1 (0.50) MAPTRAB9AL3MBTL1CASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8822724-B2 Method for producing carboxylic acid amide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-09-02 US disclosed
EP-2599769-A1 METHOD FOR PRODUCING CARBOXYLIC ACID AMIDE Sumitomo Chemical Company Limited (JP) 2013-06-05 EP disclosed
US-20130123505-A1 METHOD FOR PRODUCING CARBOXYLIC ACID AMIDE SUMITOMO CHEMICAL COMPANY, LIMITED 2013-05-16 US disclosed
EP-1281516-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2007-12-19 EP disclosed
EP-1602481-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2007-05-30 EP disclosed
EP-1203659-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-05-17 EP disclosed
EP-1602481-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-12-07 EP disclosed
US-6951171-B2 Using graft polymer on etched or anodized aluminum substrate FUJI PHOTO FILM CO., LTD. (JP) 2005-10-04 US disclosed
EP-1371500-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2005-09-28 EP disclosed
EP-1329311-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2005-09-07 EP disclosed
EP-1281516-A2 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2003-02-05 EP disclosed
US-6509132-B1 Comprises an ink-receptive image area for receiving ink during the printing process and a hydrophilic non-image area for receiving fountain solution FUJI PHOTO FILM CO., LTD. (JP) 2003-01-21 US disclosed
US-6455224-B1 SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 US disclosed
US-20020068241-A1 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2002-06-06 US disclosed
EP-1203659-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-05-08 EP disclosed
EP-1136281-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-09-26 EP disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed
EP-1031414-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-08-30 EP disclosed
US-4835312-A Production process of N-substituted amide compounds MITSUI CHEMICALS, INCORPORATED (JP) 1989-05-30 US disclosed
US-4044141-A CORONARY DILATING, SPASMOLYTIC, HYPOTENSIVE AGENTS BAYER AKTIENGESELLSCHAFT (DT) 1977-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130123505-A1 METHOD FOR PRODUCING CARBOXYLIC ACID AMIDE HCAR2, NAAA, FAAH2 MAPT 3830/4885RAB9A 2603/4885L3MBTL1 4136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.