Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | INSR | P06213 | 3/20 | 0.40 |
| ▸ | IGF1R | P08069 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5176203 | 0.83 | ARG1 (0.46) | ARG1KDM4EMEN1POLBGAA | |
| SCHEMBL5177243 | 0.81 | KDM4E (0.50) | ARG1KDM4EMEN1POLBGAA | |
| SCHEMBL5175298 | 0.81 | ARG1 (0.46) | ARG1KDM4EMEN1POLBGAA | |
| SCHEMBL5176872 | 0.81 | KDM4E (0.44) | ARG1KDM4EMEN1POLBGAA | |
| SCHEMBL5174298 | 0.78 | POLB (0.49) | ARG1KDM4EMEN1POLBGAA | |
| SCHEMBL6756755 | 0.77 | GHSR (0.46) | GHSRIGF1RLOXLOXL3LOXL2 | |
| SCHEMBL5174651 | 0.77 | BACE1 (0.44) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL5174531 | 0.77 | ALPL (0.49) | ARG1KDM4EMEN1POLBGAA | |
| SCHEMBL5175693 | 0.76 | KDM4E (0.52) | ARG1KDM4EMEN1POLBGAA | |
| SCHEMBL5174945 | 0.76 | GAA (0.45) | ARG1KDM4EMEN1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070017040-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | PROCTER & GAMBLE COMPANY, THE | 2007-01-25 | — | — | US | claimed |
| EP-1746088-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | Wella Aktiengesellschaft (DE) | 2007-01-24 | — | — | EP | claimed |
| US-20070017040-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | PROCTER & GAMBLE COMPANY, THE | 2007-01-25 | — | — | US | disclosed |
| EP-1746088-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | Wella Aktiengesellschaft (DE) | 2007-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070017040-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | KRT18, ALDH7A1, MKI67 | ARG1 171/4885GHSR 3804/4885KDM4E 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.