Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ARG1 | P05089 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722041 | 0.83 | MAPT (0.53) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL2990588 | 0.83 | ARG1 (0.56) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL5721945 | 0.82 | RAB9A (0.56) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL5176203 | 0.81 | ARG1 (0.46) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL5176205 | 0.81 | ARG1 (0.46) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL5175693 | 0.79 | KDM4E (0.52) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL19242051 | 0.76 | F2 (0.61) | KDM4EGAAMAPTRAB9AHDAC1 | |
| SCHEMBL5175457 | 0.76 | ALDH1A1 (0.56) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL5175187 | 0.75 | KDM4E (0.52) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL5176333 | 0.75 | RAB9A (0.52) | KDM4EMEN1POLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070017040-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | PROCTER & GAMBLE COMPANY, THE | 2007-01-25 | — | — | US | claimed |
| EP-1746088-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | Wella Aktiengesellschaft (DE) | 2007-01-24 | — | — | EP | claimed |
| US-20070017040-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | PROCTER & GAMBLE COMPANY, THE | 2007-01-25 | — | — | US | disclosed |
| EP-1746088-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | Wella Aktiengesellschaft (DE) | 2007-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070017040-A1 | 2-Amino-5-aminomethyl-phenol derivatives and agent for coloring keratin fibers comprising these derivatives | KRT18, ALDH7A1, MKI67 | KDM4E 160/4885MEN1 4845/4885POLB 672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.