SCHEMBL5176271

SCHEMBL5176271

CN(C)C(=O)C=CC(N)=O

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.40
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA4 P43681 1/20 0.40
DDAH1 O94760 1/20 0.32
ALDH1A1 P00352 2/20 0.32
TSHR P16473 2/20 0.32
FGFR4 P22455 1/20 0.32
LMNA P02545 1/20 0.30
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4779558 1.00 CHRNB2 (0.40) CHRNB2CHRNB4CHRNA3CHRNA4DDAH1
SCHEMBL1029179 1.00 CHRNB2 (0.40) CHRNB2CHRNB4CHRNA3CHRNA4DDAH1
SCHEMBL1700958 0.85 CHRNB2 (0.48) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL1577796 0.85 CHRNB2 (0.48) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL1577795 0.85 CHRNB2 (0.48) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL8936205 0.79 CHRNB2 (0.47) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL29462203 0.79 CHRNB2 (0.47) CHRNB2CHRNB4CHRNA3CHRNA4TSHR
SCHEMBL29737040 0.77 ALDH1A1 (0.33) ALDH1A1
SCHEMBL29394029 0.75 CHRNB2 (0.44) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL156117 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140194589-A1 WATER-DISPERSIBLE AMPHOTERIC POLYURETHANE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN REINFORCING CONCRETE JIANGSU RESEARCH INSTITUTE OF BUILDING SCIENCE CO. LTD (CN) 2014-07-10 US claimed
EP-2730595-A1 WATER-DISPERSIBLE AMPHOTERIC POLYURETHANE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN REINFORCING CONCRETE Jiangsu Sobute New Materials Co., Ltd. (CN) 2014-05-14 EP claimed
US-20140194589-A1 WATER-DISPERSIBLE AMPHOTERIC POLYURETHANE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN REINFORCING CONCRETE JIANGSU RESEARCH INSTITUTE OF BUILDING SCIENCE CO. LTD (CN) 2014-07-10 US disclosed
EP-2730595-A1 WATER-DISPERSIBLE AMPHOTERIC POLYURETHANE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN REINFORCING CONCRETE Jiangsu Sobute New Materials Co., Ltd. (CN) 2014-05-14 EP disclosed
EP-1281516-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2007-12-19 EP disclosed
EP-1602481-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2007-05-30 EP disclosed
CN-1260263-C Preparation of amphoteric polyurethane resin and products thereby and amphoteric resin composition NAT STARCH CHEM INVEST (US) 2006-06-21 CN disclosed
EP-1203659-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-05-17 EP disclosed
EP-1602481-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-12-07 EP disclosed
US-6951171-B2 Using graft polymer on etched or anodized aluminum substrate FUJI PHOTO FILM CO., LTD. (JP) 2005-10-04 US disclosed
EP-1371500-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2005-09-28 EP disclosed
US-6379863-B1 LAMINATING HYDROPHOBIC POLYMER ON SUBSTRATE; HEATING TO MAKE HYDROPHILIC; DURABILITY; REDUCED BLEMISHES; STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 2002-04-30 US disclosed
CN-1332205-A Radiation-sensitive resin composition JSR CORP (JP) 2002-01-23 CN disclosed
EP-1136281-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-09-26 EP disclosed
US-6153352-A OBTAINED BY LAMINATING ON A SUBSTRATE A LAYER OF HYDROPHOBIC POLYMER AND A LAYER OF HYDROPHILIC POLYMER FUJI PHOTO FILM CO., LTD. (JP) 2000-11-28 US disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed
EP-1031414-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-08-30 EP disclosed
EP-0922570-A2 Planographic printing plate precursor and a method for producing a planographic plate Fuji Photo Film Co., Ltd. (JP) 1999-06-16 EP disclosed
CN-1008101-B PROCESS OF PRODUCTION FOR POLYPHENYL ETHER ASAHI CHEMICAL IND (JP) 1990-05-23 CN disclosed
CN-87107289-A The production method of polyphenylene oxide 1988-06-15 CN disclosed