SCHEMBL5176397

SCHEMBL5176397

NC(=O)/C=C\C(=O)Nc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.68
ALDH1A1 P00352 6/20 0.68
HTT P42858 3/20 0.68
DDAH1 O94760 1/20 0.68
MAOB P27338 3/20 0.61
MMP1 P03956 2/20 0.61
MMP2 P08253 2/20 0.61
MMP9 P14780 2/20 0.61
EGFR P00533 1/20 0.61
MAOA P21397 1/20 0.61
LMNA P02545 1/20 0.59
PKM P14618 1/20 0.59
KDM4E B2RXH2 1/20 0.58
TGM2 P21980 1/20 0.57
LPAR2 Q9HBW0 2/20 0.56
LPAR1 Q92633 1/20 0.56
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
PARP1 P09874 2/20 0.54
PARP15 Q460N3 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2682631 1.00 MAPT (0.68) MAPTALDH1A1HTTDDAH1MAOB
SCHEMBL2682630 1.00 MAPT (0.68) MAPTALDH1A1HTTDDAH1MAOB
SCHEMBL2429556 0.90 ALDH1A1 (0.81) MAPTALDH1A1HTTDDAH1MAOB
SCHEMBL9840923 0.89 MMP1 (0.73) MAPTALDH1A1HTTMAOBMMP1
SCHEMBL6302448 0.89 MMP1 (0.73) MAPTALDH1A1HTTMAOBMMP1
SCHEMBL6302452 0.89 MMP1 (0.73) MAPTALDH1A1HTTMAOBMMP1
SCHEMBL7263605 0.86 ALDH1A1 (0.71) MAPTALDH1A1HTTDDAH1MMP1
SCHEMBL5713222 0.84 MAOB (0.61) MAPTALDH1A1HTTMAOBMMP1
SCHEMBL5713223 0.84 MAOB (0.61) MAPTALDH1A1HTTMAOBMMP1
SCHEMBL1683255 0.83 ALDH1A1 (0.79) MAPTALDH1A1HTTMAOBMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114316501-B Low-odor low-emission ABS and preparation method thereof 上海普利特复合材料股份有限公司 2023-11-28 CN claimed
EP-0751177-B1 Stabilizers for high nitrile multipolymers STANDARD OIL CO (US) 2002-08-28 EP claimed
JP-61022074-A None JP disclosed
JP-4169560-A None JP disclosed
JP-60109562-A None JP disclosed
JP-61093158-A None JP disclosed
CN-118665857-A Packaging method of master-scale ceramic copper-clad carrier plate 江苏富乐华半导体科技股份有限公司 2024-09-20 CN disclosed
CN-114316501-B Low-odor low-emission ABS and preparation method thereof 上海普利特复合材料股份有限公司 2023-11-28 CN disclosed
CN-114316501-A Low-odor low-emission ABS and preparation method thereof 上海普利特复合材料股份有限公司 2022-04-12 CN disclosed
EP-3546448-B1 DI-SUBSTITUTED MALEIC AMIDE LINKER FOR ANTIBODY-DRUG CONJUGATING AND PREPARATION METHOD AND USE THEREOF MABWELL SHANGHAI BIOSCIENCE CO LTD (CN) 2022-04-06 EP disclosed
WO-2022062244-A1 ENVIRONMENTALLY-FRIENDLY COLOR TPU FILM FOR USE ON FURNITURE, AND PREPARATION METHOD THEREOF 何建雄 2022-03-31 WO disclosed
JP-H04169560-A PRODUCTION OF N-PHENYLMALEINAMIC ACID MITSUI TOATSU CHEM INC 1992-06-17 JP disclosed
US-4771096-A ADDITION OF A CONJUGATED, NON-AROMATIC DIENE COMPOUND OR A DIENOPHILIC COMPOUND TO IMPROVE FLOW PROPERTIES GENERAL ELECTRIC COMPANY (US) 1988-09-13 US disclosed
EP-0121974-B1 POLYMER MIXTURE COMPRISING A POLYPHENYLENE ETHER AND OPTIONALLY A POLYSTYRENE AND/OR A RUBBER-MODIFIED POLYSTYRENE, AND ARTICLES FORMED THEREFROM GENERAL ELECTRIC COMPANY (US) 1986-12-30 EP disclosed
JP-S6193158-A PRODUCTION OF N-PHENYLMALEIMIDE MITSUBISHI PETROCHEM CO LTD 1986-05-12 JP disclosed
JP-S6122074-A PRODUCTION OF N-SUBSTITUTED ISOIMIDE MITSUI TOATSU CHEM INC 1986-01-30 JP disclosed
JP-S60109562-A PREPARATION OF N-SUBSTITUTED MONOMALEIMIDE DAIHACHI KAGAKU KOGYOSHO:KK 1985-06-15 JP disclosed
EP-0121974-A1 Polymer mixture comprising a polyphenylene ether and optionally a polystyrene and/or a rubber-modified polystyrene, and articles formed therefrom GENERAL ELECTRIC COMPANY (US) 1984-10-17 EP disclosed
US-4125398-A N-Phenyl-maleic acid amides for regulating the growth and development of plants CIBA-GEIGY CORPORATION (US) 1978-11-14 US disclosed
US-4125398-A N-Phenyl-maleic acid amides for regulating the growth and development of plants CIBA-GEIGY CORPORATION (US) 1978-11-14 US disclosed